Integrated Human Practices

"What we are doing, why we are doing it, how the world might affect our work, and how our work might affect the world."

Our core tenet of human practice is to bridge the gap between our projects and the real world and by continuously interacting with the world. During the process, we improve our products through close contact with stakeholders by gaining a deep understanding of their needs and opinions.

Our team put forward an innovative approach to execute our integrated human practice -- "5I cycle" (Inspiration, Ideation, Information collecting, Improvement and interaction, Implementation and imagination). This cycle helps ensure that we engage respectfullly and responsibility with stakeholders.


The experience of HIGREEN

"Tomato Crisis"

Higreen, a major agricultural wholesale market in Shenzhen, supplies over 90% of the city's fruits and vegetables. One day when we were buying tomatoes in HIGREEN as usual, we encountered Mr. Cheng uploading crates of tomatoes covered with strange white spots. We inquired about the situation, and Mr. Cheng, told us that the tomatoes was suffering gray mold disease. As a result, they even affected other tomatoes that were not infected during the transportation process, and led to significant financial loss.

Mr. Cheng expressed deep concern and frustration as he talked about the significant threat posed by gray mold disease to his tomato planting base -- Dacheng Xin Base. He highlighted that this disease posed the most severe challenge. Regrettably, it had even led to devastating consequences, resulting in yield reductions of up to 50%. Moreover, he lamented the lack of an effective solution to combat this persistent and damaging disease.

After listening to Mr. Cheng's concerns, our team were eager to assist him in solving this challenging issue. We conducted further research on gray mold disease in tomatoes :

Significant Threat of Gray Mold Disease : Based on 2020 FAO data, global tomato production reached approximately 189 million metric tons, with China contributing a significant 68 million metric tons. However, the devastating impact of tomato gray mold disease led to production losses ranging from 20% to 60%.Based on statistics from 2016, tomato gray mold disease annually caused more than 30 million yuan losses in China worth

Current Control Measures: physical and chemical control. Physical control methods include proper crop rotation and cultivation management practices. Chemical control is the most widely used method, involving the use of pesticides such as dimethomorph and pyrimethanil to manage the spread of the disease.

Shortcomings and Drawbacks:

  • 1. Overusing chemical pesticides tend to make the fungus resistant to drug , reducing drug effectiveness.

  • 2. Pesticide residues and emissions threaten the environment, potentially harming soil and water quality.

  • 3. The destroyed environment cost extra money to undo the effects.

Ideation and project forming

Discussing with the PI

"RNAi, Efficient and Eco-friendly"

After learning about the harmful result caused by gray mold disease, we wanted to find an efficient and environmentally friendly way to cure the disease. So, we consulted our PI, Professor Mo Beixin, who made great achievements in botanical research. Upon hearing our needs and ideas, Professor Mo shared us with valuable insights, suggesting that RNA interference (RNAi) technology could be a potential solution. Also it has many advantages:

1.Precision: RNAi technology precisely targets and silences harmful pathogen genes for highly focused control.
2.Efficacy: It effectively reduces disease severity by inhibiting crucial pathogen genes.
3.Non-Genetic: RNAi avoids genetic alterations, relying on natural mechanisms for temporary gene silencing.
4.Safety: It is safe, as it doesn't introduce foreign genes or alter host genomes, minimizing risks.
5.Environmentally Friendly: RNAi naturally degrades, leaving no lasting environmental residues.

Communicatng with Farmers

"Early Prevention is Crucial"

In March, Mr. Cheng invited us to visit the Dacheng Xin base. We went on a field trip, learning from tomato grower Ms Wang that farmers rely heavily on field observation. They predict potential plant diseases by closely monitoring weather, environmental conditions and plant growth. This allows them to take actions to spray pesticide in advance.

For producers, the more yielding, the better. They not only hope to effectively treat diseases, but also hope to achieve early prevention. This approach safeguards crop health, reduces disease impact on yield and quality, ensuring better economic returns.


"Establishing Our Initial Project Design"

After in-depth discussions with PI Professor Mo and field trips to the Dacheng Xin Tomato Base, we did broad brainstorm to put forward our initial disease control strategy. Our initial strategy combines prevention and treatment measures to effectively solve the probelm of tomato gray mold disease, ensuring both yield and quality.

By integrating preventive actions and timely treatment, we took every stages of gray mold disease into consideration, minimizing the risk for tomatoes to be infected by the gray mold disease. This approach ensures the and economic returns and sustainability of agriculture. We will develop specific plans based on this strategy to tackle the issue of tomato gray mold disease.

Expert Interviewing

"Positive Response Towards Initial Project Design"

Once we formed our initial disease control strategy, we sought advice form Professor Xiaojie Li, vice president of Shenzhen Graduate school Chinese Academy of Agricultural. Sciences. Professor Li highly commended our project, noting that: 'RNA pesticides are the future of the pesticide industry.' He highlighted that RNA pesticides, known for their efficiency and environmental friendliness, are considered the 'third revolution in the pesticide field,' receiving extensive attention and support from national and agricultural stakeholders.

Professor Li also fully endorsed the plant immunity component of our project. He emphasized the pivotal principle in plant protection, 'prevention is better than cure.', underscoring the importance of proactively prevention to minimize their impact on crops. Professor Li's opinions encouraged us and showed that our initial strategy is of great significance in the agricultural field.

Information collecting

After developing our initial project, we want to assess the practical feasibility of our disease control strategy in real-world scenarios. Consequently, we conducted interviews with stakeholders in the tomato industry to learn about their needs and worries regarding the gray mold disease control strategy.

We hightlight what each stakeholder most concern with towards the usage of pesticides below.

Agricultural Producers
Farmers are responsible for tomato cultivation, pest control, and harvesting, and they are the users of pesticides.

what they call for: Convenient to Use

Tomato Sellers
They serve as a bridge within the supply chain, facilitating the transfer of agricultural products from producers to end consumers.

what they call for:

Ministry of Agriculture
The Ministry of Agriculture are responsible for disease prevention, food safety oversight, and supporting farmers with technology .

what they call for:
Environmentally Friendly
Convenient to Use

Consumers' selective purchasing decisions drive producers and the supply chain towards meeting consumer demands.

what they call for:
No pesticide residues
Environmentally Friendly

 Agricultural Producers

We visited many planting bases and communicated with local farmers to understand the current commonly used pest control methods, as well as their attitudes and needs regarding pesticide use.

Ms. Wang

a farmer at the Dacheng Xin Tomato Base

Ms. Wang shared valuable insights with us. She explained how farmers rely on careful observations of weather, environmental conditions, and especially plant growth to anticipate the potential onset of plant diseases. They take measures like applying pesticides in advance to minimize the chances of plants being affected by diseases.

Ms. Wang's proactive approach provided a valuable perspective for our initial project design, leading us to consider the use of plant immunity for early prevention.

Ms. Wang

About Gray Mold Disease: Ms. Wang mentioned that gray mold disease is a common issue in the tomato fields she manages. Additionally, diseases like early blight frequently occur, causing her significant distress.

Prevention and Control: When facing gray mold disease, Ms. Wang primarily relies on chemical pesticides for control. She informed us that she typically relies on her experience for early prevention. For example, since gray mold disease tends to occur in low-temperature and high-humidity conditions, she proactively sprays pesticides under such weather conditions to prevent it. This proactive prevention approach is crucial because once gray mold disease breaks out, it spreads rapidly. At that stage, pesticide application may not effectively control it, leading to significant crop reduction and economic losses. Ms. Wang's emphasis on early prevention provided us with valuable insights.

Concerns About Chemical Pesticides: Ms. Wang also mentioned that most pesticides develop resistance after a few applications, and she cannot use the same pesticide repeatedly. She further explained that some pesticides require mixing, which is challenging for her as she is unsure of the correct blending ratios. Additionally, some pesticides have strong odors that can cause dizziness if she is exposed to them for an extended period.

Mr. Liang

a farmer in Boluo County

He mentioned that the main diseases in his tomato orchard are gray mold and powdery mildew. In disease control, crop rotation and chemical methods are primarily employed. Chemical pesticides need to be used alternately to reduce pests' resistance to them

Regarding our treatment plan, Liang emphasized that farmers are most concerned about its effectiveness, followed by cost considerations.

Mr. Liang

Regarding gray mold disease: Mr. Liang is a farmer who manages a five-acre tomato field, which operates as a pick-your-own farm during the tomato season. He faces common issues with diseases like gray mold and powdery mildew in his crops. To tackle these problems, he uses methods like crop rotation and high-temperature sterilization.

Regarding pesticides: When it comes to pesticides, Mr. Liang and other farmers prioritize safety. They prefer using low-toxicity pesticides and follow advice from trusted suppliers. They also rotate between different types of pesticides to prevent resistance.Mr. Liang shared that after pesticide spraying, there's usually a waiting period before harvesting. This waiting time can lead to economic losses, so he values effective treatments that minimize this downtime.

Regarding our treatment solution: Mr. Liang's main concern is its effectiveness in managing diseases. He's willing to invest a bit more if a treatment can provide good results, prioritizing effectiveness over cost. This aligns with our goal of offering practical and efficient solutions to farmers like Mr. Liang, ensuring healthy crops and successful harvests.

Hong Chuangjiang

Technician at Jiangnong Ecological Agriculture Company

Hong's innovative disease management concept emphasizes "treat when there is a disease, prevent when there is none." He focuses on prevention, using microbial agents and organic fertilizers early on, and later, biological agents to adjust soil microbes. Regarding chemical pesticides, he limits the use of the same pesticide to three times due to resistance development.

He strongly supports the use of biological pesticides and appreciates our treatment plan, aiming for low or zero pesticide residues in his agricultural products.

Hong Chuangjiang

Preventive Measures: Greenhouses, insect-proof nets, and smoke control are physical agricultural measures that help protect crops from pests and diseases. These methods are widely used in agricultural production to ensure the healthy growth of crops.

Pest and Disease Management: Mr. Hong Chuangjiang has his own philosophy, which is "treat when diseased, prevent when healthy, and combine Eastern and Western medicine." This philosophy emphasizes the importance of timely treatment for infected plants and proactive prevention of diseases. Preventive measures are considered crucial because they can determine whether crops will be threatened by diseases in the later stages.

During the early stages of crop growth, microbial agents and fertilizers are mainly used for prevention, which helps enhance the plants' immune systems. In the later stages of crop growth, microbial agents are employed to adjust the microbial community in the soil, maintaining soil health.

Regarding the use of chemical pesticides, a restrictive strategy is typically followed, limiting the number of times a particular pesticide is used. This strategy aims to reduce the development of pesticide resistance and enhance the effectiveness of pesticides.

For plants already infected with diseases, isolation methods are employed for management. However, due to the large-scale cultivation, inspection work becomes relatively challenging. Developing an effective identification system could potentially improve the efficiency of disease detection and management.

Smart agriculture Smart agriculture is also widely adopted in orchards, utilizing techniques such as greenhouse cultivation, drip irrigation, and digital smart management. Data-driven agriculture management has enabled integrated water and fertilizer management, significantly reducing labor costs. Integrated water and fertilizer systems dissolve fertilizers in irrigation water, enhancing fertilizer efficiency. Despite current challenges related to data accuracy, this field still holds tremendous potential for improving agricultural production efficiency and crop quality.


Guide and Grower at Dacheng Xin Tomato Planting Base

Mr. Cheng discussed tomato cultivation and the key issue of gray mold disease in his fields. They currently rely on chemical pesticides for control, but it's not very effective and leads to substantial losses. He highlighted the need for expert guidance in pesticide use. Farmers often mix pesticides, reducing their effectiveness, and the precise dilution is a challenge for them.

Mr. Cheng emphasized his concern about the importance of having user-friendly pesticide application methods that farmers can easily use. Secondly, he is highly concerned about the effectiveness of pesticides to controll tomato gray mold disease.

Mr. Cheng

The Millennium Tomato Farm at the Dachengxin Company covers an extensive area of six hundred acres, with two hundred acres personally managed and cultivated by Mr. Cheng. Additionally, Mr. Cheng imparts his extensive cultivation experience to farmers in neighboring villages, providing them with valuable technical guidance for growing cherry tomatoes.

Regarding the issue of gray mold disease: Mr. Cheng explained the tomato cultivation process and the primary diseases affecting his tomato fields. Gray mold disease is the predominant ailment in his tomato fields, and they currently employ chemical pesticides for control. However, the effectiveness of this method is somewhat limited, resulting in substantial losses.

Concerning pesticide application: Mr. Cheng informed us that pesticide application usually requires the assistance of knowledgeable technicians. He often provides technical guidance to local farmers in nearby villages. He observed that some farmers lack an understanding of pesticide usage rules. Despite the recommended application rates on packaging or in instruction manuals, certain farmers occasionally add pesticides excessively based on their subjective preferences. This leads to increased pesticide residue in crops and, in some cases, contamination of the farmland environment. Furthermore, for pesticide mixtures, farmers lack clear guidance on appropriate proportions for mixing.

Regarding Polycobead: We explained our product design and treatment plan to Mr. Cheng. He appreciated the user-friendliness of our product, particularly the convenience of the quantitative encapsulation method using beads. As for our treatment plan, he expressed that his primary concern was its effectiveness. As long as it can provide effective pest control, he would be very willing to use our product.

 Tomato Sellers

We visited many markets and communicated with sellers to learn about consumer's habits and preferences, as well as their views on pesticide residues.

Cheng Jiabo

Sales Representative at Dachengxin Agricultural Company

He discussed the challenges in tomato procurement and transportation. Tomatoes often develop gray mold disease before transport, risking the infection of the entire batch during transit. Additionally, agricultural products must undergo pesticide residue testing in the market, exceeding limits can lead to unsellable batches and economic losses.

He hopes to effectively control gray mold disease in tomatoes or prevent its spread during transportation. Regarding pesticides, he seeks low residue levels and cost-effective solutions

Cheng Jiabo

Regarding gray mold disease: Mr. Cheng informed us that he not only sells tomatoes but also has his tomato farm upstream in the industry. Gray mold disease is a significant issue faced by his tomato farm. It can manifest both before and after the fruits set, making detection and treatment extremely challenging. Currently, there are no effective methods for detection or treatment. The primary approach is to prevent its spread by burning infected plants.

Once gray mold disease appears after fruit setting, it spreads rapidly within the crop. While greenhouse cultivation can reduce the incidence of the disease, it comes at a high cost and takes two years to recoup the investment.

Although harvested fruits may not initially exhibit symptoms, there is still a risk of fruit rot during transportation due to the presence of gray mold spores. This can lead to significant losses. Furthermore, gray mold disease is highly contagious, exacerbating the potential damage to crops.

Regarding biopesticides: We also inquired about Mr. Cheng's views on biopesticides. He mentioned that his primary concern is the cost. While biopesticides are environmentally friendly, their higher prices can lead to an increase in the overall production cost of tomatoes.

Mr. Huang

The owner of Shenzhen Jinsui Vegetable Wholesale Store

Mr. Huang shared that he sells tomatoes from greenhouses and open fields. Greenhouses provide year-round harvests and disease prevention. He also mentioned organic vegetables, grown with organic fertilizers and strict quality standards, which come at higher costs but appeal to environmentally conscious consumers in the growing economy.

Regarding our treatment solution,He believes that an eco-friendly pest control method can promote the growth of organic vegetable production, making them more affordable to consumers.

Mr. Huang

Regarding tomatoes: Mr. Huang primarily sells vegetable tomatoes, which he sources from various locations based on the tomato season. He informed us that these tomatoes are grown both in greenhouses and open fields. Greenhouse cultivation allows for year-round harvesting and is less susceptible to diseases.

About organic vegetables: Mr. Huang also discussed organic produce with us. He explained that organic vegetables cannot be sprayed with pesticides, which can sometimes result in less visually appealing appearance. Organic farming relies heavily on organic fertilizers, and the certification standards are stringent, leading to higher production costs and selling prices. However, as the economy continues to develop, organic vegetables are gaining popularity due to their environmentally friendly nature and superior taste, and the consumer base for organic produce is expanding.

Opinions on our treatment solution: An effective green treatment approach can further promote the development of organic vegetables, making more people willing to invest in such produce.

 Ministry of Agriculture

We visited the agricultural department and communicated with government officials to learn about the regulations for pesticide management and the government's views and support for new technologies.

Li Yonghong

Chief Researcher at Shenzhen Agricultural Science and Technology Promotion Center

Ms. Li provided insights on tomato diseases, pesticide usage, policies, and pesticide residue testing regulations. She discussed biopesticides and challenges in agriculture. She also explained technology adoption and government innovation promotion efforts.

Ms. Li's belief in biopesticides as the future of agriculture aligns with our project direction. She also discussed essential procedures for successful implementation of new agricultural technologies, offering valuable guidance for our project planning and execution.

Li Yonghong

Shenzhen Agricultural Science and Technology Promotion Center has primary responsibilities encompassing agricultural technology advancement, crop quarantine, seed management, biotechnology safety, new variety promotion, and pesticide/fertilizer/seed regulations.

The Agricultural Development in Shenzhen: Professor Li Yonghong informed us that agriculture in Shenzhen and its surrounding areas is diverse, with a focus on leafy vegetables. Various cultivation models such as greenhouses and pick-your-own farms are prevalent. Tomato cultivation exists in the region but on a smaller scale, with a majority of pick-your-own farms and small-scale farmers. Pest and disease issues, including gray mold, sour rot, and powdery mildew, are common, especially during the fruiting stage of tomatoes. Typically, meteorological monitoring and empirical predictions are used, with limited direct detection methods.

Management of Pesticides by Agricultural Authorities: The sale and usage of pesticides are subject to government regulations, with specific qualifications required for pesticide sales. Different categories of pesticides with varying toxicity levels are subject to different management measures. The government promotes the scientific use of pesticides and provides guidance to farmers on the appropriate timing and methods of application. Additionally, the government is concerned about the impact of pesticides on soil and takes measures to reduce soil pollution. For large-scale cultivation, the government entrusts specialized agencies to provide agricultural pest control services to improve efficiency and effectiveness.

Views on Biopesticides: Professor Li Yonghong mentioned that the advantages of biopesticides lie in their environmental friendliness and safety. However, they come with higher costs and slower effects, requiring advance prediction and forecasting. The government can establish certification standards and collaborate with agricultural enterprises to conduct large-scale cultivation experiments, using data to prove the safety and effectiveness of biopesticides, thereby gaining consumer trust.

Significance of Promoting Biopesticides: The significance of promoting biopesticides lies in meeting modern society's demands for environmental protection and the quality of agricultural products, with promising market prospects. Through government guidance, promotion, the establishment of certification standards, and collaboration with the market, consumers are more willing to purchase agricultural products cultivated using biopesticides.

Regarding Genetically Modified Organisms (GMOs): Professor Li also shared her views on GMOs, stating that GMO technology is part of technological advancement. Public concerns about GMOs primarily result from inadequate public awareness. GMO technology can be beneficial for improving crop traits but must be used correctly. In China, strict regulations and labeling requirements are in place. Agricultural authorities conduct GMO awareness campaigns. The approval timeline for GMO crops varies depending on multiple stages, and policy constraints exist.

Ma Haifeng

Chief Researcher at Shenzhen Agricultural Science and Technology Promotion Center

Mr. Ma shared insights into tomato diseases, their treatments at the demonstration field, and discussed the timing and weather conditions influencing disease occurrence. He also offered on-site crop growth observations, cultivation techniques, and shared his experiences on plant protection concepts.

Mr. Ma is optimistic about our project, viewing RNA pesticides as a promising new technology. He believes our plant immune-based treatment approach aligns with plant protection principles and stressed the need for user-friendly products, ensuring farmers' ease of use.

Ma Haifeng

Regarding the demonstration field: The center oversees various agricultural functions such as strategy development, policy formulation, quality monitoring, disaster prevention, and crop disease and pest control. Mr. Wang specializes in crop disease and pest management, offering farmers technical support through field observations, and possesses expertise in prevalent crop diseases, pests, and control measures. Mr. Ma guided us on a tour of the demonstration field and explained in detail the process of breeding new varieties and the implementation of demonstration trials for new technologies at this location.

About plant protection: Mr. Ma shared with us common tomato diseases and the medications used for treatment. He also explained the timing of disease occurrence and the corresponding weather conditions. He led us to observe the growth of some crops and planting methods on-site and shared some principles and experiences related to plant protection. He emphasized the importance of using a diversified approach to manage plant diseases and pests, maintaining ecological balance, prioritizing prevention over treatment, and using pesticides rationally to achieve sustainable agricultural production. Additionally, he mentioned the significance of regulating pesticide use in accordance with the law, improving farmers' technical skills, and ensuring food safety and environmental health.

Regarding our treatment plan: After reviewing our treatment plan, Mr. Ma expressed agreement, stating that it aligns with the principles of plant protection and represents a comprehensive approach to pest control.

Wang Rifang

Senior Horticulturist at Boluo County Agricultural and Rural Service Center

Mr. Wang emphasized that low temperatures and high humidity can trigger gray mold concerns, which can be mitigated through late-season planting. Triazole-based pesticides are commonly used against fungal diseases, but addressing resistance requires ongoing research. Farmers often use experience and weather cues for prevention, but disease prediction models show potential.

Regarding our treatment solution, Mr. Wang believes that there are obstacles to enhancing immunity with biopesticides due to farmer skepticism. So, proving the product's effectiveness is crucial.

Wang Rifang

Tomato Production Challenges: The main issues in tomato production are bacterial and fungal diseases, with a focus on bacterial wilt. Bacterial wilt spreads rapidly in hot and humid conditions and is transmitted through the soil, leading to vascular blockage and wilting.Mr. Wang mentioned that grafted tomatoes are primarily used to prevent soil-borne diseases such as bacterial wilt and Phytophthora early blight, while diseases transmitted through the air, such as late blight and gray mold, still require timely control through conventional planting measures.

Regarding gray mold: Gray mold is a common disease in hot and humid conditions. Tomatoes can be divided into early and late crops, with late planting helping to reduce the impact of gray mold. For fungal diseases like gray mold, triazole-class pesticides are currently the main method of control, providing effective and economical results.

Best Time for Pesticide Application: Mr. Wang pointed out that pesticides can be applied after the disease has occurred, but based on the basic principles of farming, farmers typically observe seedlings daily. Once a disease is detected, they immediately perform appropriate pruning and apply pesticides, which generally yields good results. Leaves affected by the disease, usually young leaves, need to be pruned because the disease can affect photosynthesis. However, it's important to note that pesticides are not a universal solution, and improper use can lead to reduced yields. In winter, the likelihood of disease infection may increase, especially under abnormal weather conditions.

Regarding Disease Prediction and Warning Models: Currently, disease prevention is primarily based on experience and meteorological factors, with early preventive pesticide use being a common practice.

About Biopesticides: Currently, there is a market for immunostimulants like aminooligosaccharides that enhance immunity. However, farmers tend to use these products less due to the lack of visible effects and cost considerations. Farmers are more inclined to use treatments for diseases that have already occurred and focus on effectiveness. Nevertheless, from a scientific development perspective, there is still a pressing demand for new technologies like biopesticides. Biopesticides may have some limitations compared to chemical pesticides, such as the environmental and storage requirements for Bacillus thuringiensis. Additionally, they require specific testing parameters.

Li Li

Department of Agriculture and Seed Promotion Boluo County Agricultural and Rural Service Center, Huizhou City

Ms. Li explained the process of promoting new technologies with government support, involving technology selection, validation, and demonstration for effectiveness. Government policies offer financial aid, research funding, and tax incentives. Authorities recommend technologies to farmers and provide training for correct adoption.

Director Li emphasized the importance of both product effectiveness and product user-friendliness for successful promotion. She expressed her willingness to support further promotion efforts if our technology proves to be mature.

Li Li

The center's responsibilities encompass various aspects of agricultural production, including formulating agricultural development strategies, planning, and policies, monitoring agricultural product quality and safety, as well as disaster prevention and crop disease and pest control.Ms. Li's primary responsibility involves conducting on-ground trials and promoting new varieties and technologies.

Regarding technology promotion: Ms. Li emphasized the strong support from the government for agricultural development and new technologies. He mentioned that technologies like RNAi need to go through a series of processes within agricultural departments, including approvals and field trials, to be implemented. The government actively supports the development of new technologies by providing financial aid, research funding, and tax incentives, among other measures. During the promotion phase, relevant departments introduce and provide training to farmers to ensure the correct use and widespread adoption of these new technologies.

As for our treatment plan: Ms. Li expressed that the government highly supports the use of biopesticides, which align with environmental conservation principles and have substantial growth potential. He emphasized the importance of the treatment's efficacy, as farmers are more inclined to use products that deliver good results. Additionally, he highlighted the convenience of product usage as a crucial factor in successful promotion. Ms.Li also mentioned his willingness to assist us in further promotion if our technology matures.

Chen Wenhui

Director of Huizhou Boluo County Agricultural Science and Technology Demonstration Center

Mr. Chen discussed pesticide sales requirements, regulatory oversight, penalties, and agricultural product quality and safety monitoring. He also emphasized the vital role of technology in rural revitalization and its significant contribution to agriculture.

Mr. Chen inquired about the treatment plan's validation, its long-term plant protection, and pesticide residues. We explained, and he stressed that actual effectiveness matters most.

Chen Wenhui

The Huizhou Boluo County Agricultural Science and Technology Demonstration Center's primary functions include experimenting with new pesticides, introducing new crop varieties and technologies, and promoting agricultural research and demonstrations.

Technology dissemination plays a crucial role in rural revitalization. Currently, many rural areas are promoting the concept of "one village, one product," with the core idea being to unite farmers and support agricultural industries to achieve prosperity in villages. Continuously exploring new industrial models is the inevitable choice for rural revitalization. Director Chen stated that our products are a vivid example of technology assisting agriculture.

Regarding pesticide usage: the current situation is that most pesticides and fertilizers are inorganic chemical products. Although there are some organic fertilizer products available in the market, their effectiveness is not ideal. Therefore, many farmers prefer to purchase inorganic fertilizers rather than choosing free organic ones. Consequently, we may need to focus on improving the effectiveness of our products, especially if the cost can be relatively high while ensuring excellent results. Currently, the country is actively promoting the development of organic and biological pesticides, as well as organic fertilizers.

promotion: Director Chen mentioned that when our products are ready for practical experimentation, we can use a demonstration field approach. This allows farmers to witness the product's effectiveness firsthand, and they can spread the word among themselves. This is considered the most effective way of promotion.

Yin Zaobin

Director of Pesticide Residue Detection Center, Boluo County Agriculture Bureau

Director Yin emphasized the strict requirements and procedures for pesticide sales. These measures help ensure the quality of agricultural products and safeguard consumer health.

Director Yin highly appreciates our biopesticide, seeing great potential in it due to its approximately 30% profit margin in the pesticide industry. Effective results and farmer trust are essential for success, and biopesticides offer a safer alternative to chemical pesticides.

Yin Zaobin

The main responsibility of Boluo County Agriculture Bureau's Pesticide Residue Detection Center is to test pesticide residues to ensure the quality and safety of agricultural products, thereby ensuring compliance with regulations and consumer health. We would like to inquire with Director Yin about the current pesticide residue detection standards and sampling criteria.

Views on biopesticides: The teacher believes that biopesticides offer greater safety. For example, while herbicides like Paraquat are highly effective, they pose significant health risks to humans. Consequently, liquid formulations have been adjusted to have an irritating odor to prevent misuse. However, these measures have not completely eliminated incidents of self-harm, leading to a gradual phase-out. In contrast, our biopesticides have promising prospects. Unlike fertilizers and other products, our pesticides still hold high value.

Requirements for pesticide sales: Pesticide sales require a license and compliance with various conditions and training. Purchasing pesticides involves identity registration through a specialized platform. Licenses typically need to be renewed every five years, and past penalties may necessitate reapplication. Additional requirements may include maintaining records, township-level inspections, and regular enforcement checks.


We communicated with consumers at supermarkets to understand their consumption habits and their views and attitudes towards pesticide residues. In the process, we also discovered that consumers have misconceptions about new technologies. This has prompted us to carry out educational campaigns to eliminate these misunderstandings.

Ms. Guo

28 years old

Ms. Guo mentioned that younger consumers prioritize vegetable and fruit prices and convenience, while older consumers are more concerned about food safety and quality, especially pesticide residues. These differing considerations affect their purchasing choices, inspirating the importance of surveying different age groups.

We also introduced our biopesticide to Ms. Guo. She expressed that she would be very willing to purchase such products if they didn't significantly raise the prices of agricultural products and if they improved the taste of the produce.

Ms. Guo

Ms. Guo was randomly interviewed during our visit to the Dabanqiao Market in Nanshan District, Shenzhen. Dabanqiao Market is a daily market where local residents purchase vegetables and fruits. It is home to more than 100 vendors.

Shopping Habits: The individual usually uses Meituan for grocery shopping but decided to visit the farmer's market on this occasion for its convenience and cost-effectiveness.The shopper evaluates groceries based on factors like value for money, pricing, and the taste of the products.

Priorities: There is no specific emphasis on organic or pesticide-free produce during this visit. The primary concern is to make practical and budget-conscious purchases.

Age Differences: The shopper acknowledges that different age groups may have varying priorities. Older individuals may place more importance on pesticide residues in groceries but will still consider price when making their purchases.

Inspriration: This also provides us with a valuable insight, which is to pay special attention to the perspectives and needs of different age groups when conducting consumer surveys. In our future consumer surveys, we have been mindful of asking about their age to observe the focus areas of various age demographics.


40 years old

Ms. Lin expressed that pesticide residues and similar concerns should be addressed by market regulations rather than consumers. She mainly considers affordability and freshness when shopping for groceries. She has concerns about genetically modified crops and avoids purchasing them. As for organic produce, she is not very familiar with it since it's only available in a few expensive supermarkets, and she doesn't actively seek it out.

We introduced the concept of biopesticides to Ms. Lin and explained that our products don't carry the risk of genetic modification.


We met Ms. Lin during a random interview at the Dabanqiao Market in Nanshan District, Shenzhen. This market is where local residents buy groceries and has over 100 vendors selling fruits and vegetables.

Primary Purchase Considerations: Ms. Lin mentioned that she typically doesn't include factors related to pesticide residues and similar issues in her purchasing decisions, as she considers it the responsibility of market regulation. When selecting food items, she places greater emphasis on affordability and the freshness of the ingredients. Regarding genetically modified crops, she usually opts not to purchase them due to concerns.

View on Organic Food: Ms. Lin believes that organic food is relatively expensive. She has limited knowledge about the benefits of organic food and may perceive no significant difference in taste and quality compared to regular food. As a result, she is not very inclined to purchase organic food.


62 years old

Mr.Qiu believes that market regulation is necessary for pesticide residue issues. He thinks it's difficult for consumers to know the pesticide usage on the vegetables they consume. He believes that there are many genetically modified fruit tomatoes in the market(which is actually a misconception on his part) and worries about the presence of genetically modified organisms.

After hearing about our product, Uncle Qiu expressed interest.His misconceptions about genetically modified products in the market also motivated us to consider providing education to address consumer misconceptions.


We met Mr.Qiu in Huaren Wanjia, a large chain supermarket in Shenzhen known for its rigorous inspection process that ensures the quality and safety of produce.

Attitude towards pesticide residues: Mr. Qiu believes that the issue of pesticide residues requires the support of market supervision because consumers often find it difficult to proactively select vegetables that meet safety standards. They lack relevant information and struggle to determine whether the vegetables they purchase are affected by pesticide residues. Therefore, he believes that promotion and the establishment of relevant standards are crucial.

Attitude towards GMOs: Holds a skeptical attitude towards genetically modified organisms (GMOs) and has misconceptions, believing that most tomatoes in the market are genetically modified

Inspiration: Mr. Qiu's misconceptions have made us realize the lack of knowledge and understanding among the public regarding new technologies. To dispel public doubts and misunderstandings about new technologies, especially when it comes to emerging technologies, scientific outreach becomes crucial. This underscores the need for broader dissemination of relevant knowledge to ensure that people have a correct understanding of new technologies and are better equipped to accept and apply them.

Ms.Fan and Ms. Li

73 years old

Huaren Wanjia, a prominent Shenzhen supermarket chain, is renowned for its rigorous inspection of fruits and vegetables, offering consumers greater confidence in quality and safety. We interviewed two shoppers.

They usually buy groceries at the local market because it's fresher and more delicious, and they occasionally come to the supermarket. She believes that pesticide residue issues are a matter for government regulation and not something the consumers can control or address. As for organic vegetables, they currently find it difficult to buy organic produce as there aren't many organic options available in the market yet.

Ms.Fan and Ms. Li

Huaren Wanjia, a large chain supermarket in Shenzhen, is known for its rigorous inspection process for the sale of fruits and vegetables, providing consumers with more assurance. This strict inspection process helps ensure the quality and safety of fruits and vegetables. We interviewed two madams who are currently shopping for groceries here.

Regarding pesticide residues: both grandmothers believe that market regulatory authorities should ensure the safety levels of pesticide residues in food. They think that consumers often find it difficult to determine on their own whether vegetables and fruits are affected by pesticide residues, and therefore, regulatory oversight and standards from relevant authorities are needed to guarantee safety.

Shopping habits for groceries: The grandmothers mentioned that they usually buy groceries at the local market because they find the produce to be fresher and more delicious. Occasionally, they may visit a supermarket for their shopping needs.

Mr. Xu

23 years old

Mr. Xu, a supermarket employee, is not highly concerned about pesticide residues and generally trusts government regulations. He mentioned that he doesn't typically purchase organic vegetables due to their higher prices.

After listening to our biological pest control solution, he expressed a positive attitude and said he is open to new technologies and approaches. However, he mentioned that older consumers may not be as receptive.He told us that it's essential to educate the public more about new technologies to dispel misunderstandings and concerns.

Mr. Xu

Regarding agricultural products: Mr. Xu personally doesn't pay much attention to pesticide residues and has trust in government regulatory mechanisms. As for organic vegetables, he doesn't typically purchase them because of their higher prices.

We explained our treatment plan to Mr. Xu, and he responded with a positive attitude. He expressed his willingness to embrace new technologies and methods, b elieving that by introducing these innovations, better results can be achieved, efficiency can be improved, or existing challenges can be addressed. This positive attitude is often instrumental in driving innovation and development, leading to the success of projects or programs.

reflection:Mr. Xu believes that the younger generation is more likely to embrace new technologies, but he also thinks that older consumers may not necessarily be willing to accept them. This underscores the importance of proactive communication and addressing concerns when promoting new technologies. In our future consumer surveys, we will actively explain the principles of our technology and considerations related to safety to consumers.

Ms. Qin

40 years old

Ms. Qin expressed her strong concern about pesticide residues and her preference for purchasing vegetables from large supermarkets, which she believes offer better quality control. While she's interested in organic vegetables, she doesn't buy them regularly due to their higher prices, and she is not very open to genetically modified products.

After introducing our biological pest control solution, Ms. Qin expressed optimism about our product. She hopes that adopting biological pest control won't significantly raise vegetable prices and stressed the importance of effective regulation and safeguards for new technologies.

Ms. Qin

Regarding pesticide residues: Ms. Qin is very concerned about pesticide residues and their potential impact on food safety and health, especially for children and the elderly. Faced with this concern, she tends to prefer buying organic food or products labeled as pesticide-free because she believes these products meet her requirements for food safety

In addition, Ms. Qin is more inclined to shop at large supermarkets because she believes that these supermarkets typically have stricter quality assurance measures and can provide more reliable food supplies.

Regarding our biological control solution: Ms. Qin remains optimistic about our product. However, she expresses a concern that adopting biological control methods should not significantly increase the prices of vegetables. She also emphasizes the importance of having reliable oversight and safeguards in place for new technologies. This indicates her desire for a balance between adopting innovative techniques and ensuring affordability and safety in the agricultural sector.

Improvement and interaction


After in-depth discussions with various stakeholders related to tomatoes, we discovered that different stakeholders had varying concerns regarding the pesticide. These made us realize that we had not adequately considered these needs during the early stages of project design!

After thoroughly understanding the needs and priorities of the stakeholders involved in the tomato industry, we carefully analyzed and evaluated our project. Based on the valuable feedback received from stakeholders, we realized the importance of making specific improvements and adjustments to align with their values and requirements.

So we improved and adjusted our project to meet with the values and need they are prioritizing. After understanding the needs of the stakeholders involved in tomatoes, we made improvements to our project in five key areas to meet their requirements.


"More effective"

Overcoming bottlenecks to improve effectiveness

Agricultural Producers:
Mr. Cheng: "I believe the most important thing about pesticides is their effectiveness. If pests and diseases disappear after using pesticides, we are happy."
Mr. Liang: "Chemical pesticides nowadays develop resistance after just a few applications. I hope we can have effective pesticides."
Mr. Hong Chuangjiang: "We also use some biopesticides, but they take longer to show results. I hope biopesticides in the future will work faster and be more effective."

Ministry of Agriculture :
Researcher Ma Haifeng: "For your product, you must have ample experimental data to prove that your treatment is better than other pesticides. Only then will farmers trust your product, and the agricultural department will promote it."
Director Chen Wenhui: "The most important thing about pesticides is whether they work well or not. If they don't work well, farmers won't be willing to use them."

"Agro-Knowledge Conference"
"Agro-Knowledge Conference," themed "Future Pesticides Driven by Cutting-Edge Technology, Leading a New Journey of Green Innovation," brought together experts, representatives from the pesticide industry, academia, research, and capital. Distinguished figures like Lv Yuping, General Manager of Longping Bio, Professor Yang Guangfu from Huazhong Normal University, Tang Xueming, Chairman of Silicon Arrow Technology and so on were invited to collectively explore the commercialization of future pesticide technologies driven by cutting-edge advancements.

Our team participated in this conference and learned about the three main bottlenecks in the commercialization of RNA pesticides:

  • 1. RNAi molecules may not efficiently enter target cells and function.

    2. RNAi may have weak target effects.

    3. The production of RNAi molecules relies heavily on cell fermentation, making it difficult to reduce costs.

To make our treatment solution more effective and meet the expectations of producers and the agricultural department, we proposed our own solution to improve the efficient entry of RNAi molecules into target cells, as well as reducing the potential for off-target effects and providing a more sustained effect.

The figure explains the principles of CPP (the picture was drawn by YiXi Wang)

The figure explains the principles of CPP (the picture was drawn by YiXi Wang)

Using CPP (Cell-Penetrating Peptides) to improve delivery efficiency: We employed KH9-BP100 (a CPP) combined with shRNA. By spraying CPP-shRNA onto tomatoes infected with B. cinerea, shRNA, with the assistance of CPP, can enter plant cells more efficiently. This enhances the delivery efficiency of biomolecules into plant cells.

Bi-ShRNA providing a more sustained effect: However, by using specific sequences to link shRNAs targeting different mRNAs, the resulting bi-shRNA molecules can be processed into various siRNAs, each with a distinct function. This approach allows for a lower effective dose compared to traditional siRNA/shRNA, reducing the potential for off-target effects and providing a more sustained effect.

Please refer to the detailed content in Proof of Concept and Engineering success


Multiple Measures to Ensure Safety

Ministry of Agricultural :
Researcher Li Yonghong: "Chemical pesticides nowadays have a significant environmental impact. Your product must ensure that it doesn't have any adverse effects on the environment."
Minister Yin Zaobin: "One of the reasons for the discontinuation of paraquat is the high number of suicides by consuming pesticides. A good product should consider its safety for human health."
Horticulturist Wang Rifang: "The government is currently advocating for environmental protection. Environmental safety, human health, and the absence of pesticide residues are all aspects your product needs to excel in."

Ms. Qin: "I usually buy groceries from large supermarkets for some added assurance. I'm particularly concerned about pesticide residues exceeding the limits and also worry about genetically modified products."
Mr. Qiu: "We don't know how many pesticide residues are in the vegetables available in the market. It's a big concern. I also avoid purchasing genetically modified foods."
Mr. Xu: "I'm quite optimistic about biopesticides. They are more environmentally friendly and harmless to humans."

Everyone is deeply concerned about environmental safety and human health. We also considered safety-related issues during the initial project design. It's for safety reasons that we chose RNA interference (RNAi) and spray-induced gene silencing (SIGS) using exogenous dsRNA for treatment, which have the following safety advantages:

  • 1.Specific Targeting: It exclusively targets and silences essential genes of B. cinerea, causing no harm to other organisms.
    2.Environmental Friendliness: RNAi molecules are easily degraded, making them environmentally friendly and free from pesticide residues.
    3.Non-GMO: Unlike genetic modification technologies, RNAi-based biopesticides do not result in permanent changes in plant gene expression and are controllable.

Choosing Environmentally Friendly Bacillus subtilis : In triggering plant immunity, we selected Bacillus subtilis as the carrier to express immune-inducing factors. Bacillus subtilis is one of the most widely accepted plant probiotics and is environmentally friendly.
Constructing a Suicide Switch for Safety: To prevent our engineered bacteria from spreading and surviving in the fields, we designed a suicide switch to further ensures the safety of the product in the environment.

Please refer to the detailed content in Design

"More Affordable"

Cost Reduction through Automation Hardware

Agricultural Producers:
Mr. Liang: "We are concerned about pesticide prices. If they are too expensive, us farmers won't be able to afford them."
Mr. Cheng: "For this over 100-acre land, one pesticide spray costs me around 4,000 RMB. This price is acceptable, but if pesticides become too expensive, it won't be cost-effective."
Mr. Wang "Pesticides are essential, and we use them a lot, so I usually don't choose expensive ones."

Tomato Sellers:
Mr. Cheng Jiabo: "As business owners, we are quite price-sensitive. If your pesticides are too expensive, it raises production costs, which can impact the overall profitability of our agricultural operations. Therefore, we prefer pesticides that strike a balance between effectiveness and affordability, as long as they meet our needs and are accepted by consumers."
Mr. Wang: "Pesticides should primarily be practical and affordable, not too expensive. If they are accepted and recognized by the general public, we are willing to accept them. What we sell also depends on what consumers like."

Price is a concern for both farmers and sellers. In the early stages of development of RNA pesticide, our product cannot be as inexpensive as chemical pesticides. However, we aim to reduce production costs as much as possible to make eco-friendly and affordable products accessible to everyone. Therefore, we have designed hardware to explore the possibility of large-scale production cost reduction.

An Automated Equipment for Large-Scale Production of shRNA Molecules through a Cell-Free Method: We designed and constructed an automated hardware system suitable for large-scale synthesis of shRNA molecules. The automated production process of shRNA molecules is established by programming the microcontroller. The system can be operated by non-scientists and can be applied in non-laboratory environments. It aims to improve the convenience of shRNA production while reducing associated costs and opening up possibilities for further expansion of production.

Please refer to the detailed content in Hardware

"More User-Friendly"

Polycobead - Easy Application for Effective Disease Control

Ministry of Agricultural :
Minister Li Li: "Your product must be suitable for farmers' use, simple, easy to use, and easy to store. This is crucial for widespread adoption."
Researcher Li Yonghong: "Some pesticides can be very complicated to use, which discourages farmers and may lead to misuse. It would be better if your product is designed to be straightforward for farmers to accept."
Researcher Ma Haifeng: "User-friendliness is essential. How do you plan to ensure farmers can use the two formulations in your project? A simpler design might be better."

Agricultural Producers:
Mr. Cheng: "Pesticide application can be really troublesome. Every time, I have to request technicians to help. Some pesticides can't be mixed, or they become ineffective when mixed. It's also a hassle to calculate the right proportions. Often, I'm not sure how much to add, and it's a real headache."
Mr. Liang: "Mixing pesticides is indeed a technical task. Every time, I have to spend a lot of time reading the instructions, and there are many precautions. It's really cumbersome."
Mr. Hong Chuangjiang: "Sometimes, I don't even know how to mix pesticides, so I also hope that pesticide application can be made simpler and more convenient."

In our communications with farmers, we found widespread pesticide misuse in the agricultural sector.
Firstly, some farmers apply pesticides excessively, deviating from recommended dosage, which leads to overuse and environmental pollution. Secondly, farmers are often uncertain about how to correctly mix and use multiple pesticides, resulting in losing effectiveness.

To address these challenges and make pesticide application more user-friendly, we drew inspiration from laundry detergent beads. We decided packaging our product in a form with fixed dosage , encapsulating it within a single bead. We would then provide guidance to farmers on the number of beads for treating and preventing tomato gray mold disease. These lead to the design of our product -- POLYCOBEAD.

Polycobead uses polyvinyl alcohol (PVA) to encapsulate our CPP-shRNA formula and engineered Bacillus subtile by simply placing the designed small beads in a specific volume of water. They dissolve quickly, allowing direct field spraying. It has the following advantages:

  • 1.Ease of Use and Precise Application: The drug preparation process in Polycobead is accurately mixed in accordance with scientific proportions, without complex preparation or farmer mixing. Dissolve the beads in water and use them.
    2.Extended Shelf Life: the liquid environment inside the bead contains glycerin, which helps to extend the storage life.
    3.Environmentally Friendly: The PVA film selected by Polycobead has good biocompatibility and degradability. No harm to the environment.

Please refer to the detailed content in Engineering

"More Precise"

Accurate Modeling for Targeted Spraying

Agricultural Producers:
Mr. Cheng: "There's a problem that troubles me. You see, I manage over 100 acres of land. If I find gray mold disease in one area, how large an area should I spray with pesticides to prevent its spread? Spraying the entire 100 acres is costly, but spraying too little might not effectively prevent it."
Mr. Hong Chuangjiang: "Usually, when I discover a disease, I have no choice but to spray pesticides across the entire field to ensure prevention, even though it can be quite expensive."

Ministry of Agriculture:
Li Yonghong: "Agriculture is increasingly shifting toward large-scale farming, but it also poses some challenges. For instance, on several hundred acres of land, when a disease occurs in a particular area, how much pesticide should be sprayed to effectively control it?"
Mr. Chen Wenhui: "Even in my demonstration field, we sometimes encounter diseases, often limited to a specific region. Without timely control, the disease can quickly spread to every region."

In response to these issues, we've developed two models to effectively guide the practical application of Polycobead:
RNAi Dosage Optimization Model:
By applying optimal control and optimization theories, we optimize the cost function, guiding farmers to use RNAi pesticides optimally for disease control, product quality, and yield while minimizing costs.

Pesticide Application Range Model:
This model simulates disease development patterns under field conditions to predict the effective application area and quantity of pesticides required when diseased plants are discovered. Its aim is to minimize costs and environmental impact while effectively controlling disease spread.

Please refer to the detailed content in Model

RNAi Dosage Optimization Model RNAi Dosage Optimization Model
Pesticide Application Range Model Pesticide Application Range Model


Our team attaches great importance to safety and responsibility, so we have taken a series of measures to ensure that our POLYCOBEAD product complies with legal and societal requirements. We have carefully analyzed the legal framework concerning the use and production of microbeads. Additionally, we actively engage with communities, environmental organizations, and consumer groups to address their concerns and educate them about our solutions. Through these measures, we ensure that our POLYCOBEAD product not only meets legal requirements but also aligns with societal expectations and values.

Legal Analysis

During discussions with Chief Researcher Li Yonghong from the Shenzhen Agricultural Promotion Center in China, we learned that expanding the scale of product testing during the trial phase and bringing a product to market require compliance with relevant laws and policies. This includes ensuring the safety of trials, adherence to testing standards, and consideration of the product's safety and compliance with health and environmental standards. These regulations and policies are crucial for the commercialization of technology and industrial development.

Therefore, we wrote a document titled "Legal Analysis - Investigation of Polycobead Application under Existing Laws" to conduct a thorough examination of relevant regulations and policies. This was done to clarify the legal standards that our product needs to adhere to, particularly in the context of emerging technologies like RNAi and novel plant immune agents. This effort has laid a robust legal compliance foundation for the future development of our product, Polycobead.

The Proposal of Chinese RNA Pesticide Industry Standard

Our product is initially planned to ernter the market in China. However, we discovered that China currently lacks clear classification and standardized regulations for RNA pesticides. This highlights significant legal and regulatory challenges in the RNA pesticide sector in China, emphasizing the urgent need for applicable regulations and standards to ensure safety and sustainability in this emerging field.

To avoid misuse of RNA pesticide, we develop sufficient countermeasures to mitigate such risk by putting forward -- "The Proposal of Chinese RNA Pesticide Industry Standard "

Collaboration and Guidance from expert

After drafting the "Proposal for RNA Industry Standards in China," we proactively reached out to Ms. Li Yonghong and Dr.Jin, the researchers at the Shenzhen Agricultural Science and Technology Promotion Center, seeking further guidance and advice. Ms. Li Yonghong expressed a positive response to our initiative and believed that our proposal has the potential to effectively promote the development of regulations and standards in the field of RNA pesticides in China.

Ms. Li Yonghong outlined the steps required to advance our proposal. First, we must submit it to the Market Supervision Administration and the Shenzhen Standards Promotion Association for review and approval. We'll then collaborate with industry experts to gain recognition. Next, we'll initiate the standard declaration process, including expert review and certification. Finally, we'll gather public and business feedback for widespread acceptance.

We will continue to work within this framework, driving the development of regulations and standards in the field of RNA pesticides in China .

T.O.M.A.T.O Alliance

"how do we balance the interests
between our project and the communities negtively impacted"

The emergence of new products and technologies will inevitably have an impact on the traditional pesticide industry, affecting the interests of them. We noticed that chemical pesticides still dominate the majority of the pesticide market. Considering their interests and for the stable development of the pesticide industry, we have established the T.O.M.A.T.O-Technical Alliance (the Technology-Oriented Modernization of Agriculture-Targeted Organization). Through technology sharing and experience exchange, we aim to lead traditional enterprises in transforming and upgrading, avoiding unnecessary market competition and minimizing conflicts between new and old products to achieve mutual progress.

In addition to the product technology alliance, we propose the concept of the T.O.M.A.T.O-Thought Alliance (Thought-Oriented Modernization of Agriculture-Targeted Organization) . Because expect to the market aspect, the successful implementation and widespread adoption of the products also rely on the involvement of various stakeholders such as farmers, consumers and government. Farmers directly determine its sales, consumers' attitudes impact the market, and governments' policies have a significant influence on the development path of the products. Therefore, establish a Thought Alliance is meaningful. We hope to rally the power of knowledgeable individuals from various sectors to promote awareness of using biopesticides. Besides focusing on product and market aspects, we aim to raise people's attention towards green agriculture and ecological protection, forging ahead towards a blueprint for sustainable agriculture.

Please refer to the detailed content in Entrepreneurship

Popular science summer camp

Through conversations with consumers, we've found that many have concerns and misunderstandings about new technologies due to a lack of understanding. This led us to realize that for Polycobead to be widely accepted, we need to explain the principles of the new technology and educate consumers to dispel their concerns and misconceptions.

As a response, we organized an educational summer camp where we explained the principles of RNA pesticides and plant immunity to consumers, addressing their misconceptions and helping them understand Polycobead's new technologies and advantages. In a subsequent survey, the majority of consumers showed significant interest and a willingness to support our product. This consumer affirmation positions our product for future wide use and acceptance.

Implementation and imagination

Close Our Loop

"Revisiting Dacheng Xin Tomato Farm"

In late September, as tomato seedling cultivation began at Dacheng Xin Tomato Planting Base, our experiments gained initial success. At this pivotal juncture, we revisited the farm in Shanwei City and engaged in in-depth discussions with Mr. Cheng, Mr. Cheng, who owns over 200 acres of tomato fields, and Mr. Fan, who is responsible for sales.

We introduced our Polycobead product's curing strategy and designing concept at the tomato planting base. We emphasized Polycobead's advantages, highlighting its environmentally friendly, residue-free biocontrol measures for effective gray mold control. We also stressed its user-friendliness, enabling precise application with no need for complex preparation or mixing,.

After our explanation, Mr. Cheng expressed strong interest in Polycobead. He considered it was a convenient, precise, and environmentally friendly solution to the grey mold controlling, which is also capable of controlling the situation of ovsrusing pesticide.

Mr. Fan emphasized the intense market competition and consumers' high demands for food quality and safety. He believed that Polycobead could enhance tomato quality, reduce pesticide residues, and increase their product's competitiveness.

After hearing their feedback, we were greatly encouraged to know that our product has the potential to address the challenges they face and bring benefits to their agricultural production. We will continue to work diligently to bring Polycobead to the market as soon as possible, meeting everyone's needs and our mutual goal for sustainable agriculture.

From Unit to Union

After conducting legal research and standard formulation, we have created an orderly market environment for polycobead. Then, we assessed the development potential of POLYCOBEAD in a long run from both market and societal perspectives. We made a business plan and strategic formulation, proposing the "From Unit to Union" development plan. Starting from relevant units, we aim to connect each group and form a unified union—T.O.M.A.T.O Alliance.

Firstly, we analyze the interests, needs, and backgrounds of each unit, examining the acceptance of different groups towards polycobead.

After gaining a comprehensive understanding of each unit and the pesticide industry, we unite each group to form the T.O.M.A.T.O Alliance, including Technology-Oriented Modernization of Agriculture-Targeted Organization (Technical Alliance) and Thought-Oriented Modernization of Agriculture-Targeted Organization (Thought Alliance).

The emergence of new products is likely to pose a threat to the traditional chemical pesticide industry. Therefore, the establishment of the T.O.M.A.T.O Technology Alliance aims to avoid conflicts between new and old products in the market competition. We call for advanced biotechnology companies to join the research and production of biopesticides and to encourage traditional enterprises to undergo transformation and upgrading.

New products and technologies will inevitably face many cognitive challenges in the process of entering the market. Therefore, we have established the T.O.M.A.T.O Thought Alliance, uniting each unit, engaged in science communication and provided proposal suggestions. We aim to improve the awareness of all units involved, clearing obstacles for the promotion of products and the advancement of Green and Sustainable Agriculture.

Please refer to the detailed content in Entrepreneurship


Proposed by our team SZU-China, the “5I” cycle is bound to provide the guidance for other teams.

Under the guidance of the 5I principle, we completed the closed loop of Human Practice work. We fully improved the feasibility of the project in the process and delivered our own value.

"what we are doing, why we are doing it, how the world might affect our work, and how our work might affect the world."

Now we are sufficient to answer these question!

We learned about the harm of gray mold to the agricultural industry from the field inspection of the Dacheng Xin Planting Base, and continuously investigated the needs and attitudes of stakeholders during the process of project improvement , and made "5I Principle" to meet the actual needs . And finally generate our product —— POLYCOBEAD.

At the same time, we pay attention to the connection and impact between products and the world , and convey our values and attitudes of safety and responsibility through laws and regulations and industry standards.

Then, we visited the tomato base again, investigated the feasibility of the product at the actual production site , collected user attitudes, and popularized the product concept.

Through the detailed investigation of the whole process of the stakeholders involved in the use of pesticides, we put forward the concept -- From Unit to Union . We formed the TOMATO Technology Alliance , which balance the interests between traditional pesticide companies and advanced biotech companies. At the same time, we have formed the TOMATO Thought Alliance , which unites people from all walks of life to improve recognization of the product and raise awareness of sustainable agriculture .

The names and photos of the citied individual are used with their specific permission and informed consent.