Since May of last year, after being diagnosed with pancreatic cancer, Qiqi underwent an open surgery. Subsequently, in June, she commenced her first round of chemotherapy, concluding the third round in August. She is currently preparing for the fourth round of treatment. The chemotherapy process is exceedingly painful, and the degree of side effects varies due to differences in individual physical conditions and medication dosages. Qiqi experiences acute drug reactions, with symptoms of nausea and vomiting occurring on the same day as the chemotherapy.
In addition to the physical pain, patients also have to cope with immense psychological trauma. Throughout the course of treatment, when the side effects become unbearable or the treatment's effectiveness is poor, and cancer recurrence becomes a cruel reality, patients may exhibit feelings of sadness, silence, depression, helplessness, and despair. Some may even refuse to eat or drink and experience severe insomnia. At the same time, the patient's family members, facing emotionally unstable patients, also feel extremely helpless and struggle to come to terms with the impending departure of their loved ones.
Education about life and death
In the process of preparing for iGEM, Peking2023 's project focuses on pancreatic cancer-targeting engineered bacteria. When addressing our audience, we inevitably delve into topics related to disease and mortality, as the two are closely intertwined. What is life? What is death? How do young people in Chinese society confront the topic of life and death? These are questions that we are deeply concerned about. Initially, we distributed questionnaires to young people and discovered that when facing illness, most individuals in Chinese society fear that they or their loved ones might succumb to it. However, they consciously avoid discussing the topic of death. When it comes to talking about death, only seven percent of respondents felt at ease. At the same time, most people contemplate the meaning of life and death, yet they lack relevant knowledge about life and death education. Finally, the vast majority believe that society and schools should provide life and death education for adolescents. Therefore, through our participation in iGEM education initiatives, we hope to contribute to the progress of life and death education in Chinese society.
Questionnaires Statistics
Due to traditional cultural taboos and other factors, research on death-related issues in mainland China is relatively limited, and there is a significant lack of life and death education. However, the significance of life and death is not diminished by folk taboos, and we cannot afford to avoid these important issues. Our team members initially reached out to students from Peking University's School of Social Sciences, particularly those in the Yan Fu Program, for interviews on the choices related to life and death. Later, we invited Dr. Lei Aimin, who first acknowledged the importance of our recognition of life and death education, and discussed the current situation of its implementation in China.
Dr. Lei's Interview
Peking2023 published the interview content, which generated significant responses from fellow students. Consequently, we decided to invite Dr. Lei to Peking University to conduct a lecture on the subject of thanatology. Dr. Lei began his lecture by discussing the concepts of cardiac death and brain death, providing a comprehensive understanding of what the process of "death" entails for individuals. He also shared the five stages of psychological development in terminally ill patients, ranging from denial and anger to eventual acceptance. We were also fortunate to interview Professor Ke Yang, during which we discussed the current situation and challenges of providing end-of-life care to terminally ill patients in China.
Professor Ke's Interview
High school students education
Lectures
Later on, we began conducting lectures for high school students nationwide, educating them about synthetic biology while also sharing knowledge about life and death education. We hoped that these students could gain a better understanding of life and no longer fear the occurrence of death. The education group launched synthetic biology education projects in middle schools, covering 13 provinces(or municipalities), Hong Kong and Macau.
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A question asked during a high school lecture
Labs
We aim to provide high school students with the opportunity to personally experience the iGEM competition process, fostering their interest in synthetic biology and inspiring them to aspire to contribute to improving human health in the future.
Education for College Students
We collaborated with various departments to host on-campus booth activities, where college students played games related to finding primers and understanding the principles of restriction enzymes. We also promoted the iGEM competition, and the students had a highly positive response to these activities. We also organized lectures on thanatology to help students in the School of Life Sciences recognize the importance of the 'life and death' issue. This aimed to ensure that they do not become solely absorbed in a technocratic mindset. In addition to enriching their sense of life's meaning, they will also better respect the lives of experimental subjects in future research. We also collaborated with six other universities to organize a popular science conference on microbiome-based cancer therapy. This allowed more students to experience the applications of synthetic biology in the field of medicine and ignited a collective desire for scientific exploration.
Handbook of Microbial Mediated Tumour Therapy in synthetic Biology
We cooperated with BNUZH-Chin, Pekinghsc, JLU-NBBMS,Tsinghua and Guangxi-U-China, compiled the Handbook of Microbial Mediated Tumour Therapy in Synthetic Biology.