SynBio Talk
We firmly embrace the idea that science remains incomplete until it is
effectively conveyed. As such, we have dedicated our best endeavors to
the art of scientific communication. This facet of our work is vital in
not only disseminating knowledge to the broader public but also in
fostering the development of scientific communities. In pursuit of this
goal, we have shared our insights on combating cervical cancer with the
wider population and have encouraged aspiring young scientists to equip
themselves for future challenges.We achieved this through the following:
1. We conducted a workshop for informing aspiring students about what
synthetic biology is and the overwhelming impact of it in our future.
This also served as a means of spreading word about iGEM and the amazing
work done by budding scientists in this field. The workshop had a
specific focus on imparting knowledge about synthetic biology as a
multidisciplinary field to a group of aspiring engineers. Through this
workshop, we aimed to challenge the notion that biology solely revolves
around cells and organisms. Instead, we aimed to instill in the
participants the fundamental principles of biological systems and their
application in designing genetic circuits, programmable cells, and
engineering complete metabolic pathways, among other aspects.
We elaborated that iGEM holds profound importance for college students
as it offers a unique opportunity to bridge the gap between academic
knowledge and real-world application. Engaging in the International
Genetically Engineered Machine competition allows students to gain
hands-on experience in synthetic biology, honing essential laboratory
skills and project management abilities. Ultimately, participation in
iGEM empowers students to develop practical skills, inspires a passion
for science, and prepares them for future careers in biotechnology and
synthetic biology.
The importance of SynBio was highlighted as it offers innovative
solutions to pressing global challenges, such as healthcare,
environmental sustainability, and food security. SynBio enables the
design and engineering of biological systems, leading to the creation of
novel biotechnological applications, from advanced medical treatments
and sustainable biofuels to biodegradable materials. It also inspires
interdisciplinary collaboration, fosters ethical considerations, and
drives economic growth by spurring entrepreneurship and innovation. As a
catalyst for progress, SynBio empowers us to address the complex issues
of our time and chart a course towards a more sustainable and
technologically advanced future.
During the workshop, students had the opportunity to witness our
previous years, CRISPRLY, and current year's project, NeuraSense, in
order to help the understand the scope of the field.
Instagram Engagement
Social media is one of the most effective ways to reach a large group of
people, especially the current generation. Hence, we utilized digital
media through articles and surveys to expand our outreach to a broader
spectrum of society. We came up with interesting, easy-to-read and
informative posts about synthetic biology to get people interested in
this wonderful field. We wanted to debunk the myths and demystify the
facts around synthetic biology which say its only about the biology. We
believe that doing so is vital in order for interdisciplinary research
to be encouraged.
School Visit
Team iGEM IIT Roorkee as part of its extensive Human Practices Outreach
conducted a workshop on 11th October 2023 in ABN School, Roorkee on
Scientific Communication
The workshop aimed to foster understanding of the emerging discipline of
synthetic biology (SynBio) and its extensive potential for addressing
local and global challenges through innovative and eco-friendly means.
An enthusiastic team consisting of four of our core team members
undertook the workshop and discussed a variety of topics including
SynBio, iGEM, Applications of SynBio, Machine Learning and its
applications, Our Previous projects, the current problem statement and
our solution. Everyone of our team members explained in simple yet
informative terms the previously mentioned topics to capture the
attention of the students there. We even focused on our current years
problems statement, raising awareness about dementia and Alzheimer's
Disease. The audience was mainly composed of students from 9th to 12th.
During our team's discussions about the contemporary, captivating
applications and the future potential and innovative scope of synthetic
biology (SynBio), the students were enthralled, and we had their
complete attention. We acquainted the students with the exciting SynBio
projects in an effort to kindle the flame of innovation in their minds
and impress upon them the idea that young people can pioneer this
emerging field. In summary, the experience was truly enriching. The
school authorities were exceptionally supportive and contributed to the
seamless execution of the workshop. The students, in particular,
relished the workshop, and their innate curiosity shone through as they
posed numerous high-quality, unconventional questions, which our team
eagerly addressed.
Workshop
During the workshop, we sought to challenge the conventional perception
that biology is solely concerned with cells and organisms. Instead, we
aimed to instill the foundational principles of biological systems in
the context of designing genetic circuits, creating programmable cells,
and engineering complete metabolic pathways, among other aspects.
Students had the opportunity to witness the remarkable progress in
technology, particularly in genome sequencing and editing, DNA and
protein engineering, which have been the driving forces behind the
growth of synthetic biology.
In addition to these core concepts, the workshop delved into the realm
of biosensors, a prominent outcome of synthetic biology, and explored
their applications in various industries, including food production,
diagnostics, and pharmaceuticals. To provide a practical understanding
of the advancements in synthetic biology, we also conducted a
comparative analysis between the traditional non-directional gene
cloning technique and the newer BioBRICKs approach. This comparison shed
light on how emerging technologies are addressing the limitations of
older methods.
In line with our commitment to cutting-edge research and innovation, our
team is currently engaged in an exciting project related to Alzheimer's
disease. We have developed a groundbreaking Point of Care diagnostic
kit, which is based on the detection of biomarkers in saliva using DNA
aptamers. This innovative approach represents a significant leap forward
in the early diagnosis of Alzheimer's disease and holds the potential to
revolutionize how we approach the detection and management of this
condition, which was also discussed in the workshop.
We were delighted to have over 125 participants in attendance, and the
feedback we received following the workshop was overwhelmingly positive.
All India iGEM Meet(AIIM)
Our team participated in the All India iGEM Meet held at IISER BHOPAL,
an annual regional conference that gathers iGEM teams from across India.
This event provided us with a valuable opportunity to interact with
fellow iGEM teams, as well as engage in collaborative discussions.
During the conference, we were able to present an abstract of our
project and receive valuable insights and feedback from iGEM
ambassadors, experts in the field, and other participating teams. Over
the course of the conference, we attended several talks by iGEM
ambassadors, synthetic biology experts , fireside talk with IGEM Asia
oceania promoter, Sana Jalili and workshop on phylogeny modelling by Dr.
Parimal Kar, associate professor at IIT Indore providing us valuable
guidance on system design and simulation of biological circuits, and
predicting outcomes, feasibility and limitations. We also attended the
IGEM startups event which provided a platform for various IGEM teams to
pitch their project as a startup in front of entrepreneurs who gave them
valuable feedback. On the second day, we had the privilege to attend an
amazing session called Navigating the Scientific Landscape: THE IGEM
METHODOLOGY by Dr. Lavanya Bhagavatula, founder and CEO of Anvaya
Biotech which gave us valuable insights about IGEM through her
experience. The line-up truly put a lot of new ideas into perspective
for us and left us discussing new opportunities for the weeks that
followed.
The judging sessions held significant relevance for our team. Throughout
these sessions, we had the privilege of listening to teams from
different regions of India as they presented their iGEM project ideas
and detailed the extent of their research and experimental progress.
Following our presentation, we engaged in an interactive
question-and-answer session with a diverse panel of judges.They praised,
and reaffirmed a lot of our ideas, particularly for the Wet-Lab portion
of our kit. The judges made a lot of emphasis on the importance and
social relevance of our kit and gave us the motivation we needed to
really push for the execution of our Proposed Integrated Human
Practices. During our poster presentation, the judges brought certain
aspects of our kit under scrutiny.