L O A D I N G . . .

Safety

Project Safety

Project safety encompasses the measures we've taken to ensure the safe and responsible execution of our iGEM project. Key elements of our project safety include:

Risk Prevention

Project safety is central to our iGEM project, and one of the key safety features we integrated into our system is the resveratrol-induced lysis system. This system allows for controlled lysis and cell death in the engineered bacteria by adding resveratrol. The inclusion of this resveratrol-induced lysis system serves as an additional layer of safety, preventing the potential leakage of bacteria into the external environment and minimizing any risk to human health.

The resveratrol-induced lysis system is a critical component of our biocontainment strategy. In situations where containment measures might be compromised, the ability to trigger cell lysis with resveratrol offers a fail-safe mechanism to ensure that our engineered organisms do not persist outside of controlled laboratory conditions. This proactive measure enhances the overall safety of our project and minimizes the potential for unintended consequences.

By integrating the resveratrol-induced lysis system into our project design, we have taken a significant step in ensuring the responsible and secure implementation of our research. This additional safety measure demonstrates our commitment to minimizing risks and maintaining the highest standards of safety in synthetic biology.

Fig 1. The Resveratrol-induced Bacteria Lysis System

Safety Protocols

We established strict safety protocols and guidelines for working with genetically modified organisms (GMOs) and potentially hazardous materials. These protocols were followed diligently throughout the project's duration.

Fig 2. Safety Protocols

Biocontainment

Our project involved the use of genetically engineered organisms. To prevent their release into the environment, we implemented robust biocontainment measures, ensuring that our modified organisms were confined to the laboratory setting.

Fig 3. Strictly follow the safety protocols

Ethical Considerations

We recognized the ethical implications of our work and ensured that it adhered to all applicable ethical guidelines, including considerations for potential dual-use concerns.



Lab Safety

Lab safety focuses on the well-being of our team members and other individuals working in the laboratory. Our lab safety measures include:

Safety Training

All team members received comprehensive training in laboratory safety, covering topics such as the handling of hazardous materials, safe practices, and emergency procedures.

Fig 4. Lab Safety Training

Personal Protective Equipment (PPE)

We strictly enforced the use of appropriate PPE, including lab coats, gloves, safety goggles, and respirators, where necessary, to minimize the risk of accidents and exposure.

Fig 5. Personal Protective Equipment

Emergency Response

We had established emergency response protocols in place, including evacuation plans, safety showers, eye wash stations, and fire extinguishers, to address any unforeseen incidents promptly.

Fig 6. Emergency Response

Regular Inspections

Routine safety inspections were conducted to identify potential hazards and address them promptly.

Fig 7. Regular Inspections

Collaboration with Institutional Safety

We collaborated closely with our institution's safety officers to ensure that our work complied with all relevant safety regulations and guidelines.


Conclusion

The safety of our project and the well-being of our team and the broader community were paramount throughout our iGEM project. Our commitment to project safety and lab safety ensured that our research was conducted responsibly and ethically, minimizing risks and promoting safe practices. We are dedicated to the ongoing pursuit of scientific excellence, driven by our commitment to safety and responsibility.