"Cancer has been a leading cause of death, accounting for nearly one in six deaths worldwide each year.
In the early 20th century, the concept of "oncolytic bacteria" was initially formed.
We changed EcN' s Tsr chemoreceptor protein into Helicobacter pylori' s Tlpc Protein
which can responds to lactic
acid,so that EcN has the ability to target lactic acid.
To achieve a better treatment, we put a sword on this brave trooper, which is an antibody-coupling drug. ADC
drugs have
two parts: antibody and cytotoxic drugs. Like a missile divided into a guidance and a warhead.
In the future, we hoped that oncolytic therapy and synthetic biology
can be better developed, bringing new possibilities
for the treatment of tumors.