1.  Overview/Intro

Lack of awareness of ‘antibiotics’ and ‘antimicrobial peptides’ was revealed in our questionnaire within the community. Therefore, we held a popular science speech targeting children aged 7-12, to help them gain a better understanding of those professional terms and emphasize the significance of our project simultaneously.

What’s more, we also created social media accounts to share some educational information and carried out the online education by sharing the PPT as well as utilizing the Tencent app for the online meeting and recorded the whole process so that other interested students could watch it later.

 

2.  Offline education activities

Title: Popular Science Activity on Antimicrobial Peptides and Antibiotics for Children

Introduction:

l  Background: Our community lacks awareness of "antibiotics" and "antimicrobial peptides" concepts

l  Goal: Popularize these concepts to children aged 7-12 and emphasize the importance of our project

 

Methods:

l  Use diagrams, storytelling, and roleplaying to explain professional terms to students new to biology

l  Roleplay on antibiotic abuse, antimicrobial peptides, and superbugs to set the context

 

Since our audience was students new to biology, abundant illustrations and story-telling approaches were utilized when explaining expertise vocabulary. In the beginning, we started with a role play about the overuse of antibiotics, and the function of antimicrobial peptides and superbugs. As expected, the role play was conducive to activating the atmosphere. Also, it offered students fundamental knowledge of antibiotics and antimicrobial peptides. The subsequent Q&A session has proven that such an introduction is remarkably constructive for students' comprehension.

Students were actively participating in offline education activities.

 

Explaining Key Concepts:

l  Use metaphors to simplify complex terms like antibiotics and antimicrobial peptides (e.g. castle guards)

l  Explain in detail what are "antibiotics" and "antimicrobial peptides"

l  Analogies help students truly master relevant knowledge and stimulate interest in biology

 

Following was a detailed illustration of ‘antibiotics’ and ‘antimicrobial peptides’. To facilitate students’ understanding of those complex terms, numerous metaphors were adopted to make comparisons to objects like castle guards. By this means, students obtained relevant knowledge of antimicrobial peptides thoroughly. Meanwhile, their interest in biology was motivated and some even proposed becoming a biologist. As a student said in our return visit, "I am looking forward to the next biology lesson. When my mom got sick taking antibiotics, I told her it was wrong and we should see the doctor."

We were sharing .

 

Consolidating Understanding:

l  Conduct Q&A sessions to reinforce knowledge and gauge students' comprehension

l  Reward students for actively answering to encourage participation

l  Organize a drawing game to apply antimicrobial peptide concepts and analyze market prospects

 

After the conceptual explanation, a Q&A session was conducted, which strengthened their knowledge and enabled us to realize their mastery levels. Each active respondent was rewarded for inspiring participation and enthusiasm. Apart from this, a draw-and-guess game regarding the application of antimicrobial peptides was organized. We attached great importance to the topic selection, taking the application of antimicrobial peptides as the theme and analyzing its market prospects.

Takeaways:

l  Combined concepts with daily life scenarios to improve understanding and problem-solving skills

l  Introduced iGEM competitions and encouraged participation in the future

Through this game, students' divergent thinking and imagination were cultivated. The combination of antimicrobial peptides and daily life scenarios facilitated their comprehension and integration of new knowledge. Moreover, associating the functions of antimicrobial peptides with real-life issues enhanced their capability in problem-solving and logical reasoning, which may assist them in dealing with problems in daily life. Additionally, we introduced the International Genetically Engineered Machine (iGEM) competition and encouraged them to participate in the future.

 

 

Group photo with kids.

 

Education slides

Click here to see our slides -attachment 1

 

3.  Online education activities

l  Online lecture

Our team's online education record covers various aspects. First and foremost, we made a meticulous PPT for this online teaching and displayed it publicly during the lecture, enabling learners to review it afterwards. Secondly, we utilized Tencent app for the online meeting and recorded the whole process, so that other interested students could watch it later. Meanwhile, we took advantage of the transcription function embedded in the Tencent APP to transcribe the nearly one-hour speech into text, which was integrated into a document for reference, not just by attendees but also by students potentially interested in synthetic biology.

In our online lecture, we collaborated with the college iGEM team - CPU China to educate people about antimicrobial peptides, antibiotic resistance, and bifidobacteria. The primary audience was high school and college students. Throughout the science popularization, we expect to stimulate their interest in synthetic biology and take this discipline into account when selecting majors and career paths in the future.

 

 

 Our poster and slides

Click here to see our slides -attachment 2

 

l  Social media  

Additionally, our team has an account on social media that enthusiasts of synthetic biology or iGEM competitions can follow, where we update the content in real time.

Moreover, we have established accounts on social platforms such as Bilibili and TikTok  across different districts. Popular science videos regarding iGEM competition and synthetic biology are uploaded periodically, containing text, images and soundtracks corresponding to the scenes. The purpose is to help more individuals understand synthetic biology, our competition, team and products, thereby evoking their interest in this discipline or competition.

 

3.1 TikTok  Platform

By using TikTok , our team can widely publicize the knowledge of antimicrobial peptides and antibiotics, which raises awareness among the general public. In total, we published five videos on TikTok  with a total of more than 1,000 views. They are about synthetic biology, iGEM competition, the mechanisms and advantages of antimicrobial peptides, bacterial infections, and antibiotic resistance. In addition, we also talk about the severity of antibiotic abuse in the video, which can better let people understand the purpose of our invention and promote public acceptance. At the same time, we also open the comment function, looking forward to people’s discussion with us, and accept people’s suggestions to us. There are videos explaining what is iGEM competition and what is synthetic biology in plain language so that the public has a basic understanding of iGEM competition and synthetic biology. This also creates opportunities for young people to learn this discipline, so more innovative young people with dreams and creativity can join the iGEM family.

 

TikTok

3.2 Bilibili Platform

We created a Bilibili account and uploaded the same videos as TikTok , in order to expand the scope of our video promotion and raise public awareness of antimicrobial peptides and antibiotics. In order to explain the different concepts, our videos are always very long, and it is easier to push traffic in B ilibili, so it just makes up for the shortcomings of TikTok  only giving segment video traffic.

Bilibili

3.3  Wechat Official Account

We created a WeChat Official Account in order to let more people know about AMPs. The WeChat official account is a really efficient way for people around us to get information directly. We first introduced our team, basically where we are from. Then we had articles related to AMP scientific facts and methods to use them properly. We also listed the serious issues that the infection of bacteria and the mystery in it, which aims to raise people's awareness of the serious consequences of resistance to bacteria. We had a considerably large pageview, for example, our group intro part had 114 pageviews in total.

 

 

WeChat Official Account

 

Our first popular science article delves into the historical development of the relationship between humans and microorganisms. In ancient times, humans were completely unaware of the existence of microorganisms, while bacteria quietly thrived. However, in a certain era of antiquity, a tribe suddenly fell victim to a mysterious illness, causing panic with symptoms like high fever, headaches, and difficulty breathing, all without any understanding of the culprit. As time progressed, humanity gradually became aware of the presence of bacteria and began their battle against these microorganisms. Bacterial infections encompass a range of diseases, including respiratory tract infections, gastrointestinal infections, skin infections, and urinary tract infections. The discovery of antibiotics brought hope for the treatment of bacterial infections, but over time, bacteria developed resistance to these drugs, leading to the immense challenge of antibiotic resistance. Throughout history, fascinating stories emerged, such as Alexander Fleming's discovery of penicillin and modern research into antimicrobial peptides, reflecting humanity's relentless efforts and innovations in combating bacterial infections.

 

 

part of article about the historical development of the relationship between humans and microorganisms

 

Our second popular science article about antibiotic resistance in a peaceful town. A sudden outbreak of infections caused high fevers, slow-healing wounds, and difficulties in treating common colds, painting a grim picture of antibiotic resistance quietly spreading through the town. Bacteria have grown smarter over time, learning to evade antibiotics, much like a thief deftly avoiding detection. Excessive reliance on antibiotics and their misuse allowed bacteria to master the art of resisting these drugs. To combat antibiotic resistance, we must change our behaviors and take proactive measures. This includes using antibiotics correctly, raising self-protection awareness, and intensifying scientific research to discover new treatment methods.

 

part of article about antibiotic resistance

Our third popular science article introduces another solution to the problem of antibiotic resistance - antimicrobial peptides. These small molecular peptide chains are nature's gifted defense tools to humans, capable of defeating bacteria in various ways and resistant to quick development of resistance. Antimicrobial peptides hold the promise of becoming a new option for treating bacterial infections, but solving the problem requires global cooperation and the relentless efforts of scientists. By cultivating good hygiene habits and continuously researching new drugs and treatment strategies, we can effectively curb the spread of antibiotic resistance, safeguarding human health and the future.

 

part of article about antimicrobial peptides

 

4 Conclusion

Through online and offline publicity, we help the public to popularize the abuse of antibiotics and antimicrobial peptides, so that they have a basic understanding of this. The result shows that most people do not know about the abuse of antibiotics and antimicrobial peptides. Therefore, we feel that the offline and online publicity campaigns we have implemented are necessary to further enhance public awareness of antimicrobial peptides and antibiotics.