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Collaboration

Collaboration

CONTENT
1.Collaborations we
initiated
2.Collaborations we
participated in
witch
小桌宠

After being an iGEM team, one of the biggest advantages is that we can communicate with iGEMers all over the world, through which not only helps to improve our projects, but also gain a lot from other projects, and cooperation makes the team closer at the professional level. In the process of cooperation, the team also experienced the power of unity. Unity makes our projects more professional and makes the problems we want to solve clearer.

Collaborations

we initiated

    ● Global Picture Book Project——Synbiorainbow

    Childhood autism, also known as childhood autism, is one of the most serious disorders of childhood developmental disabilities, mainly manifested by three major symptoms: social communication disorders, speech and non-verbal communication disorders, narrow interests and stereotyped and repetitive behaviors. According to the World Health Organization, approximately 1 in 160 children worldwide was diagnosed with autism in 2021. At the same time, the cause of this is not completely clear, and modern medical methods cannot fundamentally cure it.

    We work with 10 global iGEM teams (HainanU-China, OUC-China, SZU-China, HBUT-China, CAU-China, GXU-China, SDU-CHINA, BIT-China, UM-Macau, NJU-China,MIT-MAHE) Collaborate on the creation of a series of strips. Each school produces black and white graffiti picture books (unlimited in form and style) related to the project and produces a book. Contact an autistic children's agency to send a coloring book to the autistic child. Assemble the coloring results and make an eBook. It aims to help autistic children get out of difficult situations, care for children's growth, let synthetic organisms enter children's world, and give them the courage and strength to face new things.

    ● Joint lecture activities on synthetic biology

    On August 21, 2023, OUC-China and OUC-Haide presented an online synthetic biology seminar for local high school students. In the process of this conference, we not only talked about the development process of synthetic biology for them along the historical context of synthetic biology, but also explained the content of basic synthetic biology circuits such as oscillation circuits, and also explained the basic content of the projects of the two teams. In the process of this cooperation, we have also strengthened our understanding of synthetic biology, and the two teams have brought different perspectives to students, which has enriched the content of this presentation, and this cooperation is a valuable opportunity to communicate and spread synthetic biology.

    联合宣讲1 联合宣讲2

    ● Multi-school online meetings

    We held an online virtual meeting with 6 teams to introduce each other about the project and the team, as well as to exchange ideas about the collaboration in the HP part. We are fortunate to see the diversity of projects in different fields, as well as the perspectives and directions of different projects to solve problems. The SDU-China team suggested the scope of subsequent applications of medium-chain fatty acids in our project, and more subsequent products could be tried. At the same time, other teams also put forward constructive comments on our project and had in-depth discussions on future development. We are very sure that this gathering is a valuable opportunity for us to improve the project every exchange and cooperation.

    联合宣讲3

    ● Online meetings with SDU-China

    We held an online virtual meeting with Shandong University, SDU-China exhibited their microplastic degradation project, we showed the synthesis of medium-chain fatty acids and the idea of harmful substance degradation, and also understood the project advantages of their respective teams, SDU-China has made rapid progress in experiments, from which we have obtained methods to advance experiments. At the same time, there was an in-depth exchange in the modeling and hardware sections. For the Human Practice part, a proposal for further cooperation in raw material sampling is proposed. Shandong University provided us with samples of kitchen waste oil, and we provided soil samples to Shandong University for the detection of microplastics, which led to in-depth cooperation between different parts of the project.

    联合宣讲4

    ● Activity of exchanging experimental samples

    After preliminary online communication, the intention of raw material cooperation was reached online. The SDU-China team provides us with the raw materials of kitchen waste oil to synthesize medium-chain fatty acids, and we provide the SDU-China team with microplastics for easy detection and utilization. Through the scientific sampling method, the collected samples meet the experimental requirements and can be used and tested normally. This offline cooperation broadens the influence and scope of our project, and is a very valuable win-win opportunity for cooperation.

    联合宣讲5

    ● Collaboration activities with IISER Pune

    We reached out to the IISER Pune team through slack, and we provided the team with some information on the collection of used edible oil, the sources and methods of used edible oil, details of the treatment methods currently employed, and data on the production of used edible oil.

    At the same time, their team also replied to our curiosity about whether there is a problem with the use of biofuels synthesized from waste oil recovery: So currently what we have found from our research is that what limits the production of Sustainable Aviation Fuel (SAF) is the scarcity of feedstock. Used cooking oil is a potential feedstock for the same but what surprised us is that used cooking oil even though is used so widely all over the world is a limitation in producing SAF. Used cooking oil is ideal to be used as a jet fuel after hydro-processing because medium chain fatty acids after cracking and hydroprocessing give the ideal properties to the fuel such as flash poin. We reached out to the IISER Pune team through slack, and we provided the team with some information on the collection of used edible oil, the sources and methods of used edible oil, details of the treatment methods currently employed, and data on the production of used edible oil. At the same time, their team also replied to our curiosity about whether there is a problem with the use of biofuels synthesized from waste oil recovery:t, cloud point, density, viscosity etc..

    We also hope that they will be able to compare the differences in biological and chemical synthesis yields, promote a partial understanding of the project market in the process of communicating with each other, and strengthen the communication and cooperation between the two teams.

    联合宣讲6 联合宣讲7

Collaborations

we are involved in

    ● Eight Teams of Joint Synthetic Biology History Comic Series

    As one of the organizers, our team participated in the SynBio Hourstory biological history science popularization event. This activity is jointly initiated by eight iGEM teams from the University of Chinese Academy of Sciences, Lanzhou University, Beijing Normal University, Hainan University, Ocean University of China, Wuhan University, Tianjin University and Guangxi University. It aims to use the simple and beautiful form of comics to popularize the development of synthetic biology to the public, tell the historical evolution of synthetic biology, and connect comics with the major deeds of scientific history as the main line.

    This event affected a larger audience and was reported by relevant authorities, relying on social platforms such as Zhihu and Quora to simultaneously carry out forums to discuss issues related to synthetic biology, providing new knowledge and ideas for understanding problems. In this activity, it provided our team with valuable opportunities to exchange education-related knowledge, and in this activity, it was clearer how to transfer the knowledge of synthetic biology interestingly, and also provided reference for our team's educational activities.

    ● CCiC Synthetic Biology Debate Competition

    At the 10th Regional Exchange Conference CCiC, we participated in the Synthetic Biology Debate Competition, which exchanged the theme of should/should humans resurrect extinct species under the conditions of technology permitting, in which there was a discussion of ethics and the definition of bioinformatics. This debate competition is a very valuable team exchange activity, discussing the problems of synthetic biology from different perspectives, expanding the ideas of team members, and solving problems in the future.

    ● CCiC Modeling Seminar

      In the early stage of modeling, the modeling groups of Ocean University of China, Shandong University and Hainan University jointly discussed the methods used in their respective models, among which Shandong University mainly explored the spatial structure properties of proteins by establishing differential equation models and combining molecular dynamics simulation methods. Ocean University of China also uses differential equations to predict the quantitative change relationship between substances, and puts forward the idea of combining machine learning prediction, but due to the problem of insufficient amount of data, the feasibility of the scheme needs to be further verified. Hainan University wants to use machine learning pipelines to train a general, universal peptide screening model, but it is currently limited by insufficient computing power of equipment.

      For the current problems of insufficient data volume and insufficient computing power of equipment, everyone put forward their own ideas, such as increasing the amount of data through data augmentation, improving the training speed through GPU, and choosing the appropriate model to reduce the data requirements.

      All three teams have a positive attitude towards future cooperation, believing that helping each other will play a good role in promoting each other's project progress and further cooperation in the future.