People need cat!

With the increasingly affluent living conditions nowadays,

many people want a Cat as their companion.

However, Allergy to cat hair stop people adopting cat.

The allergy affect a lot

Feline allergies are a common source of allergens, affecting up to 15% of adults and children and causing symptoms such as severe asthma.

Data from the U.S. National Health and Nutrition Examination Survey indicates that Over 5 million asthma attacks occur each year,

with~350,000 emergency room visits attributed to patients sensitized and exposed to feline allergens.

Fel d 1 causes to allergy

Sensitization to the major feline allergen, Fel d 1 (Felis domesticus allergen 1), elicits IgE responses in >90% of cat-allergic individuals.

Feline allergens are produced by the sebaceous, salivary, and lacrimal glands of cats, and the highest Fel d 1 levels are found in saliva.

When cats groom themselves, Fel d 1 is transferred from saliva to their hair, and cat dander containing Fel d 1 allergen is then spread to the environment as small airborne particles.

There is an urgent need for a new scheme

Despite the prevalence and potential severity of feline allergic disease, current treatments meet a high unmet need.

Merely address the allergic symptoms (e.g., Antihistamines).

High cost and inconsistent results (e.g., Feline allergen immunotherapy).

Short active time and frequent needed (e.g.,Anti-allergy cat food).

Our Solution

To overcome the shortcomings of the current therapies against feline allergic disease we designed C.A.T: Cat Allergic Therapy.

As a novel therapy for cat allergy, the chassis bacteria, genetically programmed to adhere to the saliva pellicle of cats, produce two single-chain fragment variables (scFvs) and secrete them outside the cell. These scFvs block the immune response caused by the antigen and prevent allergies.


Adhering enables our engineered bacteria to live in the cat's mouth for an extended period of time, which shorten the treatment cost as well as time and energy.


Neutralize the Fel d 1 to stop antigens transmission. By this way, the cat allergy can be prevented before allergic symptoms occurred.


Sterilization module kill Streptococcus mutans, the main pathogen in dental plaque and prevent biofilm formation.


Specially designed suicide circuit are able to sense the change of both temperature and pH value, preventing the engineered bacteria enter cats’ digestive tract or harm the environment.

Learn more about us