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Gold Medal

Best Integrated Human Practices, Nomination

Best Part Collection, Nomination

UTokyo 2023 Project

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Our story

...Still waiting for transcription?

Transcription factor → Promoter + GOI. Do you still design like this?

Synthetic biology systems often require rapidity. We have no time to wait for transcription.

Quicker secretion for a wider range of ligands

MESA for detection and signal(in our case; protease) transductions.

Protease amplification for rapid and sufficient signal.

Inducible secretion for quick output of protein.

Description page

A slight delay means the difference between life and death

Promptness in synthetic biology is required in multiple situations.

Diagnosis, therapy, bio-manufacturing, contamination detection etc…

CRS treatment is our primary implementation.

Proposed implementation