NameTypeDescriptionDesignerRegistry
(G4S)2-LinkerCodingG4S-repeat based short linkerIgor KoopBBa_K4574024
006.11-HCCodingpcDNA3.4 vector containing anti-HBsAg heavy chain of 006-11 monoclonal IgG1 antibodyIgor KoopBBa_K4574083
006.11-LCCodingpcDNA3.4 vector containing anti-HBsAg light chain of 006-11 monoclonal IgG1 antibodyIgor KoopBBa_K4574082
108aa-GS-LinkerCodingGS-rich extra-long linker tailored for joining the antigen-binding fragments of heavy and light chains in a single-chain fragment (scFab)Melina RieplBBa_K4574023
11aa-APG-LinkerCodingAPG-repeat based short linker designed for seamless fusion of immunoglobulins to single-chain variable fragments (scFv)Igor KoopBBa_K4574020
18aa-GS-LinkerCodingGS-rich short linker tailored for joining the variable fragments of heavy and light chains in a single-chain variable fragment (scFv)Igor KoopBBa_K4574021
57aa-GS-LinkerCodingGS-rich long linker tailored for joining the antigen-binding fragments of heavy and light chains in a single-chain fragment (scFab)Igor KoopBBa_K4574022
Anti-CAIX IGVHCodingVariable heavy chain locus of the human cG250 monoclonal IgG1 antibody, which specifically targets human carbonic anhydrase 9 (CAIX)Wilex AGBBa_K4574013
Anti-CAIX IGVLCodingVariable light chain locus of the human cG250 monoclonal IgG1 antibody, which specifically targets human carbonic anhydrase 9 (CAIX)Wilex AGBBa_K4574012
Anti-HBsAg IGVHCodingVariable heavy chain locus of the 006-11 monoclonal IgG4 antibody, which specifically targets surface antigen fo the hepatitis B virus (HBsAg)Paul Anthony MacaryBBa_K4574011
Anti-HBsAg IGVLCodingVariable light chain locus of the 006-11 monoclonal IgG4 antibody, which specifically targets surface antigen fo the hepatitis B virus (HBsAg)Paul Anthony MacaryBBa_K4574010
Anti-hTfR IGVHCodingVariable heavy chain locus of the humanized hu128.1 monoclonal IgG1 antibody, which specifically targets human transferrin receptor (hTfR)Roche Diagnostics GmbHBBa_K4574009
Anti-hTfR IGVLCodingVariable light chain locus of the humanized hu128.1 monoclonal IgG1 antibody, which specifically targets human transferrin receptor (hTfR).Roche Diagnostics GmbHBBa_K4574008
Anti-IL-23A IGVHCodingVariable heavy chain locus of the human MOR-4649 monoclonal IgG1 antibody, which specifically targets human interleukin-23 subunit α (IL-23A)Centocor IncBBa_K4574005
Anti-IL-23A IGVLCodingVariable light chain locus of the human MOR-4649 monoclonal IgG1 antibody, which specifically targets human interleukin-23 subunit α (IL-23A)Centocor IncBBa_K4574004
Anti-mTfR IGVHCodingVariable heavy chain locus of the rat 8D3 monoclonal IgG2a antibody, which specifically targets mouse transferrin receptor (mTfR)Ruben J. BoadoBBa_K4574015
Anti-mTfR IGVLCodingVariable light chain locus of the rat 8D3 monoclonal IgG2a antibody, which specifically targets mouse transferrin receptor (mTfR)Ruben J. BoadoBBa_K4574014
Anti-toxin A IGVHCodingVariable heavy chain locus of the human AR-301 monoclonal IgG1 antibody, which specifically targets toxin A (hemolysin) of Staphylococcus aureusKenta Biotech AGBBa_K4574007
Anti-toxin A IGVLCodingVariable light chain locus of the AR-301 monoclonal IgG1 antibody, which specifically targets toxin A (hemolysin) of Staphylococcus aureusKenta Biotech AGBBa_K4574006
AR301-HCCodingpcDNA3.4 vector containing anti-toxin A (hemolsyin) heavy chain of AR-301 (tosatoxumab) monoclonal IgG1 antibodyIgor KoopBBa_K4574063
AR301-LCCodingpcDNA3.4 vector containing anti-toxin A (hemolsyin) light chain of AR-301 (tosatoxumab) monoclonal IgG1 antibodyIgor KoopBBa_K4574062
bGH poly(A) signalCodingBovine growth hormone termination sequence with strong polyadenylation signalIgor KoopBBa_K4574049
cG250-HCCodingpcDNA3.4 vector containing anti-CAIX heavy chain of cG250 (girentuximab) monoclonal IgG1 antibodyIgor KoopBBa_K4574078
cG250-LCCodingpcDNA3.4 vector containing anti-CAIX light chain of cG250 (girentuximab) monoclonal IgG1 antibodyIgor KoopBBa_K4574077
GCCACC KozakCodingVertebrate consensus sequence which enhances the initiation of translation in eukaryotic cells by promoting ribosome recognition and binding to the mRNA’s start codonIgor KoopBBa_K4574027
GH1 leaderCodingHuman growth hormone (somatotropin)-derived leader sequence from the GH1 geneIgor KoopBBa_K4574003
Human IGHM splice acceptorCodingCanonical 3’ (acceptor) splice site derived from the human IGHM geneIgor KoopBBa_K4574053
Human interleukin 2CodingCytokine essential for T-cell proliferation and regulationIgor KoopBBa_K4574017
IGHG1CodingHuman immunoglobulin heavy chain constant gamma (Cγ) region derived from the IGHG1 geneIgor KoopBBa_K4574019
IGHJ splice donorCodingCanonical 5’ (donor) splice site derived from the mouse IGHJ2/IGHJ3 as well as human IGHJ4/IGHJ5 geneIgor KoopBBa_K4574055
IGHV1-46 promoterCodingVH1-family human IGH promoter from human IGHV1-46 geneIgor KoopBBa_K4574050
IGHV1-51 leaderCodingHuman heavy chain (HC) leader sequence from the GHV1-51 geneIgor KoopBBa_K4574002
IGLC2CodingHuman immunoglobulin light chain constant lambda (Cλ) region derived from the IGLC2 geneIgor KoopBBa_K4574018
IGLV1-40 leaderCodingHuman variable lambda (Vλ) leader sequence from the IGLV1-40 gene — an N-terminal signal peptide associated with the lambda light chain of antibodiesIgor KoopBBa_K4574001
Left homology arm hIGH-1CodingLeft homology arm (LHA), designed to target the human IGH locus, precisely downstream of the J6 joining segment geneAlessio D. NahmadBBa_K4574041
Left homology arm hIGH-2CodingLeft homology arm (LHA), designed to target the human IGH locus, precisely downstream of the J6 joining segment gene.Igor KoopBBa_K4574043
Left homology arm hIGH-3CodingLeft homology arm (LHA), designed to target the human IGH locus, precisely downstream of the J6 joining segment geneIgor KoopBBa_K4574045
Left homology arm mIGHCodingLeft homology arm (LHA), designed to target the mouse IGH locus, precisely downstream of the J4 joining segment geneAlessio D. NahmadBBa_K4574047
Melanotransferrin peptideCodingA highly conserved 12-amino acid peptide derived from human melanotransferrin serving as a ligand for human (very) low-density lipoprotein receptor ((V)LDLR)Chaahat S. B. SinghBBa_K4574016
MOR4649-HCCodingpcDNA3.4 vector containing anti-IL-23A heavy chain of MOR-4649 (guselkumab) monoclonal IgG1 antibodyIsabel AschenbrennerBBa_K4574061
MOR4649-LCCodingpcDNA3.4 vector containing anti-IL-23A light chain of MOR-4649 (guselkumab) monoclonal IgG1 antibodyIsabel AschenbrennerBBa_K4574060
Mouse IGHM splice acceptorCodingCanonical 3’ (acceptor) splice site derived from the mouse IGHM geneIgor KoopBBa_K4574054
mutated IGH promoterCodingVH1-like mutated IGH promoter, showing 85% identity to both human and mouse VH1 promotersAlessio D. NahmadBBa_K4574052
pA-ΔIGHp-ev-SDCodingpcDNA3.4 vector containing anti-toxin A (hemolsyin) light chain of AR-301 (tosatoxumab) monoclonal IgG1 antibodyIgor KoopBBa_K4574093
pcDNA3.4-TOPO vectorPlasmid_BackboneThe pcDNA3.4-TOPO vector is a constitutive mammalian expression vector with high levels of transgene expressionInvitrogenBBa_K4574000
PHEX splice donorCodingHigh-quality canonical 5’ (donor) splice site derived from the human phosphate regulating endopeptidase X-linked (PHEX) geneIgor KoopBBa_K4574056
promoter IGHV1-62-3CodingVH1-family mouse IGH promoter from human IGHV1-62-3 geneIgor KoopBBa_K4574051
PVGLIG-LinkerCodingMMP-2 responsive linker, PVGLIG, specifically designed for selective cleavage by the tumor-associated enzyme, matrix metalloproteinase-2 (MMP-2)Igor KoopBBa_K4574025
pX458 vectorPlasmid_BackboneThe pX458 vector is commonly used in the CRISPR-Cas9 system for genome editingFeng ZhangBBa_K4574031
pX459 vectorPlasmid_BackbonepX459 vector is commonly used in the CRISPR-Cas9 system for genome editingFeng ZhangBBa_K4574032
Right homology arm hIGH-1CodingRight homology arm (RHA), designed to target the human IGH locus, precisely upstream of the intronic enhancer Eμ regulatory elementAlessio D. NahmadBBa_K4574042
Right homology arm hIGH-2CodingRight homology arm (RHA), designed to target the human IGH locus, precisely upstream of the intronic enhancer Eμ regulatory elementIgor KoopBBa_K4574044
Right homology arm hIGH-3CodingRight homology arm (RHA), designed to target the human IGH locus, precisely upstream of the intronic enhancer Eμ regulatory elementIgor KoopBBa_K4574046
Right homology arm mIGHCodingRight homology arm (RHA), designed to target the mouse IGH locus, precisely upstream of the intronic enhancer Eμ regulatory elementAlessio D. NahmadBBa_K4574048
RNA guide hIGH-1RNACRISPR guide RNA (gRNA), designed to target the human IGH locus, precisely between the J6 joining segment gene and the intronic enhancer Eμ regulatory elementAlessio D. NahmadBBa_K4574033
RNA guide hIGH-2RNACRISPR guide RNA (gRNA), designed to target the human IGH locus, precisely between the J6 joining segment gene and the intronic enhancer Eμ regulatory elementChristopher PfeifferBBa_K4574034
RNA guide hIGH-3RNACRISPR guide RNA (gRNA), designed to target the human IGH locus, precisely between the J6 joining segment gene and the intronic enhancer Eμ regulatory elementChristopher PfeifferBBa_K4574035
RNA guide hIGK-1RNACRISPR guide RNA (gRNA), designed to target the human IGK locus, precisely between the J6 joining segment gene and the intronic enhancer Eμ regulatory elementAlessio D. NahmadBBa_K4574036
RNA guide hIGK-2RNACRISPR guide RNA (gRNA), designed to target the human IGK locus, precisely between the J6 joining segment gene and the intronic enhancer Eμ regulatory elementChristopher PfeifferBBa_K4574037
RNA guide hIGK-3RNACRISPR guide RNA (gRNA), designed to target the human IGK locus, precisely between the J6 joining segment gene and the intronic enhancer Eμ regulatory elementChristopher PfeifferBBa_K4574038
RNA guide mIGHRNACRISPR guide RNA (gRNA), designed to target the mouse IGH locus, precisely between the J4 joining segment gene and the intronic enhancer Eμ regulatory elementAlessio D. NahmadBBa_K4574039
RNA guide mIGKRNACRISPR guide RNA (gRNA), designed to target the mouse IGK locus, precisely the light chain kappa constant regionAlessio D. NahmadBBa_K4574040
SacI restriction siteCodingSacI recognition site, a six-base restriction enzyme site with the sequence 5’-GAGCT^C-3’, originating from Streptomyces achromogenesIgor KoopBBa_K4574030
T2ACodingA 2A-like ribosomal skipping sequence derived from the Thosea asigna virusIgor KoopBBa_K4574026
TGATGA double stop codonCodingDouble stop codon sequence, TGATGA, ensuring enhanced termination of protein translation by providing two consecutive termination signalsIgor KoopBBa_K4574028
Truncated human EGFRCodingA truncated version of the human epidermal growth factor receptor (EGFR) polypeptideXiuli WangBBa_K4574057
XhoI restriction siteCodingXhoI recognition site, a six-base restriction enzyme site with the sequence 5’-C^TCGAG-3’, originating from Xanthomonas holcicolaIgor KoopBBa_K4574029