Introduction
The driving force for this year’s project was our hope to relieve the pain of those who are suffering from the impact of the condition known as Rheumatoid Arthritis. That’s why we did our best to design a new therapeutic option that can help control the progression of their disease, while sparing them for the side effects associated with other treatment modalities. Consequently, this would improve the quality of life of these patients, and ultimately allow them to contribute to enhancing their overall productivity in the community.
Impact grant winner:
We are very proud to have been among the 90 teams who received iGEM’s impact grant for this year. It is an honor to be considered among the projects that have a significant impact on the health and productivity of the community. This grant has really helped us during the validation in the wet-lab as it provided us with the money necessary to supply most of the chemical and reagents required to complete the wet lab workBronze medal criteria
| Competition Deliverables | Complete the following competition deliverables: Wiki, Project Promotion Video, Presentation Video, Judging Form, and Judging Session. | We presented our project in the promotion video, and the project is also fully described in the wiki pages. Additionally, in our judging form, we put the links to all pages that explain why we qualified for the medals and awards. | Find our promotion video here: AFCM-Egypt project promotion videos Our presentation video will be on the iGEM platform after the Wiki freeze. |
| Project Attributions | Describe what work your team members did and what other people did for your project using the standardized form. | On our attribution page, we documented everyone's role and executed work on the project. Moreover, anyone who helped us according to the iGEM new standards on the attributions page | Find our attributions here : Attributions | AFCM-Egypt - iGEM 2023 |
| Project Description | Describe how and why you chose your iGEM project. | On our project description page, we described every detail of our project in a concise way, with charts and illustrations that clarified our words. | Find our Project description here: Project description | AFCM-Egypt - iGEM 2023 |
| Contribution | Make a useful contribution for future iGEM teams. | We made a useful contribution to all iGEM teams. | Find our contributions here: Contributions | AFCM-Egypt - iGEM 2023 |
Silver medal criteria
| Engineering Success | Demonstrate engineering success in a technical aspect of your project by going through at least one iteration of the engineering design cycle. | We used the principles of DBTL cycle to improve the different aspects of our MSC-mRNA therapeutic approach for rheumatoid arthritis patients. | Find our Engineering here: Engineering | AFCM-Egypt - iGEM 2023 |
| Human Practices | Explain how you have determined your work is responsible and good for the world. | We made it a priority to connect with all stakeholders involved in our project, seeking their input to help refine our product. We also reached out to the public to gather their reflections and feedback on how our product could impact the world. Additionally, we ensured that the values we identified were properly integrated into our product. | Find our Human Practice here : Main human Practice | AFCM-Egypt - iGEM 2023 Integrated human Practice | AFCM-Egypt - iGEM 2023 Education | AFCM-Egypt - iGEM 2023 |
Gold medal criteria
| Excellence in Synthetic Biology | Impress the judges with your work towards three special prizes of your choice. You must demonstrate excellence in both General Biological Engineering and in at least one Specialisation. | We have done focused work on our 3 special prize choices, with a detailed focus on the 5 questions of each one in the iGEM judging handbook. | General Biological Engineering :
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