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Tomato Spotted Wilt Virus (TSWV) poses a significant challenge to tomato production, with current methods proving ineffective.

Chemical pesticides are unable to combat the virus's ability to rapidly develop resistance to these chemicals.

The use of resistant tomato cultivars has provided only partial protection, as TSWV can overcome plant resistance mechanisms through mutation.

These limitations highlight the pressing need for innovative and more sustainable approaches.

PROJECT OVERVIEW

Guarden's involves the development of a bacterially-mediated RNA interference (RNAi) mechanism to tackle Tomato Spotted Wilt Virus (TSWV).

This innovative approach aims to harness RNAi to interfere with the replication and expression of TSWV genes in tomato plants, ultimately conferring a fortified defense system against the virus, thus mitigating its negative effects on tomato crops.