Fire blight is highly contagious and difficult to control causing hundreds of acres to be cut down and burned.
Cankers are formed which allow bacteria to survive a winter till the next spring when flowers bloom.
As antibiotics have been used increasingly over the past century, resistance to these life-saving medicines grows exponentially. Phage therapy offers an exciting alternative.
Using phage Φ Ea104, we will optimize the phage to attack the fire blight bacteria.
Then we will delete an essential gene to ensure the phage does not attack other microbes in the environment.