1) There are estimated 1.93 million new colorectal cancer cases diagnosed, and 0.94 million colorectal cancer caused deaths in 2020 worldwide. The global new colorectal cancer cases is predicted to reach 3.2 million in 2040. (Xi & Xu, 2021)

2) The increase in the screening rate between 2012 and 2018 represents an additional 9.3 million adults screened for colorectal cancer, according to Centers for Disease Control and Prevention (CDC).

3) Nowadays, the treatment for colorectal cancer is expensive and health supplements are not available.

4) According to our investigation, some Cruciferous plants, like broccoli, can effectively prevent rectal cancer.