In recent years, hospital-acquired infections
(HAIs) have become an important
challenge, seriously affecting the prognosis of
patients.
The opportunistic pathogen Pseudomonas aeruginosa mainly causes severe pneumonia and sepsis, with a high incidence rate and mortality.
It is a typical hospital infection bacterium that can be isolated from various clinical specimens and hospital environments.
Blood, alveolar lavage fluid, pus……
Medical devices, other
object surfaces……
Water, air……
Unfortunately, the emergence of multidrug-resistant Pseudomonas aeruginosahas also made traditional antibacterial treatment ineffective.
The biofilm of Pseudomonas aeruginosacan resist various external environmental influences, making it impossible for antibiotics to have bactericidal effects.
Mild bacteriophages have shown great potential in disease treatment. It has extremely high host specificity and no obvious side effects and may become the mainstream method for treating multidrug-resistant Pseudomonas aeruginosainfections.
