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...happens in tomatoes.


At present, people tend to use chemical pesticides to solve the problem.

But there are still problems with their use that cannot be ignored:

PolycoBead

polycobead-rna polycobead-immu polycobead-up polycobead-down
Tomato grey mold is a specific fungal disease caused by Botrytis cinerea. SZU-China aims to combat tomato grey mold through synthetic biology.

Firstly, utilize RNAi technology to silence crucial survival genes and virulence factors of the B. cinerea , employing innovative approaches including binding cell-penetrating peptides (CPP) with shRNA to significantly treat tomato grey mold. Additionally, we will supplement this with plant immune technology by modifying Bacillus subtilis, enabling it to express immune-inducing factors such as flg22 and BvEP to trigger plant immune responses.Finally, based on the actual needs of agricultural applications, we creatively encapsulate the RNAi-based biopesticides and calcium alginate beads containing engineering B. subtilis that can trigger the immune effect of plants in a water-soluble film, forming a unique application model similar to laundry beads, which we call PolycoBead.

We hoped that this novel plant fungal disease control strategy can bring enlightenment for future biopesticide research.
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